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(1E)-2,3-dihydro-1H-inden-1-one semicarbazone, also known as 2,3-indandione semicarbazone, is a semicarbazone derivative of 2,3-indandione, a cyclic ketone with the chemical formula C9H12N2O. This off-white to yellow crystalline powder is sparingly soluble in water and is recognized for its potential pharmacological activities, such as antimicrobial and anti-inflammatory properties. It is also utilized in organic synthesis for the preparation of various heterocyclic compounds, making it a versatile compound with significant applications in both chemical synthesis and pharmaceutical research.

7461-24-7

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7461-24-7 Usage

Uses

Used in Organic Synthesis:
(1E)-2,3-dihydro-1H-inden-1-one semicarbazone is used as a reagent in organic synthesis for the preparation of various heterocyclic compounds. Its unique structure allows it to participate in a range of chemical reactions, contributing to the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
(1E)-2,3-dihydro-1H-inden-1-one semicarbazone is used as a compound with potential pharmacological activities in pharmaceutical research. Its antimicrobial and anti-inflammatory properties make it a candidate for the development of new therapeutic agents.
Used in Antimicrobial Applications:
In the field of antimicrobial applications, (1E)-2,3-dihydro-1H-inden-1-one semicarbazone is used for its potential to combat various microorganisms, which could be beneficial in the development of new antibiotics or antifungal agents.
Used in Anti-inflammatory Applications:
(1E)-2,3-dihydro-1H-inden-1-one semicarbazone is also used in anti-inflammatory applications due to its potential to reduce inflammation, which may lead to its use in the treatment of inflammatory diseases.
Used in Therapeutic Agent Development:
(1E)-2,3-dihydro-1H-inden-1-one semicarbazone is used as a starting point for the development of therapeutic agents for various diseases, given its pharmacological potential and the ongoing research into its properties and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 7461-24-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,6 and 1 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7461-24:
(6*7)+(5*4)+(4*6)+(3*1)+(2*2)+(1*4)=97
97 % 10 = 7
So 7461-24-7 is a valid CAS Registry Number.

7461-24-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (2,3-dihydroinden-1-ylideneamino)urea

1.2 Other means of identification

Product number -
Other names Indanon-semicarbazon

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7461-24-7 SDS

7461-24-7Downstream Products

7461-24-7Relevant academic research and scientific papers

Evaluation of the semicarbazones, thiosemicarbazones and bis-carbohydrazones of some aryl alicyclic ketones for anticonvulsant and other biological properties

Dimmock, J. R.,Pandeya, S. N.,Quail, J. W.,Pugazhenthi, U.,Allen, T. M.,et al.

, p. 303 - 314 (1995)

A number of aryl alicyclic ketones were converted to their corresponding semicarbazones, thiosemicarbazones and bis-carbohydrazones.Anticonvulsant activity was displayed by most of the compounds in the maximal electroshock (MES) and subcutaneous pentylenetetrazole (scPTZ) screens when given intraperitoneally to mice.However, on oral administration to rats, a marked selective activity in the MES screen only was noted.X-ray crystallography on five semicarbazones was undertaken in order to find correlations between the shapes of these molecules and anticonvulsant properties.The thiosemicarbazones displayed greater cytotoxicity to P388D1 and L1210 cells than the semicarbazones while a number of human tumors and different viruses were, in general, insensitive to representative compounds.semicarbazone/ thiosemicarbazone/ anticonvulsant agent/ X-ray crystallography/ cytotoxic agent

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