74611-55-5

Upstream product

• 6602-54-6 2-chloro-3-pyridinecarbonitrile 
• 95-68-1 2,4-Xylidine 
• 74611-48-6 2-(2,4-Dimethyl-phenylamino)-nicotinonitrile 
• 17782-10-4 2-(2,4-dimethyl-anilino)-nicotinic acid 
• 57-13-6 urea 

Downstream Products

• 74611-58-8 3-Benzyl-1-(2,4-dimethyl-phenyl)-1H-pyrido[2,3-d]pyrimidine-2,4-dione 
• 74611-57-7 3-((E)-But-2-enyl)-1-(2,4-dimethyl-phenyl)-1H-pyrido[2,3-d]pyrimidine-2,4-dione 
• 74611-56-6 1-(2,4-Dimethyl-phenyl)-3-ethyl-1H-pyrido[2,3-d]pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Optionally substituted pyrido[2,3-d]pyridine-2,4(1H,3H)-diones and pyrido[2,]pyrimidine-2(1H,3H)-ones

The present invention relates to optionally substituted pyrido[2,3-d]pyrimidine-2,4(1H,3H)-diones or optionally substituted pyrido[2,3-d]pyrimidine-2(1H,3H)-ones, i.e., compounds of Formula I: STR1 wherein: Y is --CH2 -- or --C(O)--; R1 is hydrogen or --(CH2)n --R7, wherein: R7 is aryl or heteroaryl, and n is 1 or 2, provided that when Y is --C(O)--, R7 is heteroaryl; and R2, R3, R4, R5 and R6 are hydrogen, or one is selected from lower alkyl, halo, carboxy, methoxycarbonyl, carbamoyl, methylcarbamoyl, di-methylcarbamoyl, methylcarbonyl, methylthio, methylsulfinyl, methylsulfonyl, hydroxymethyl, amino, trifluoromethyl, cyano or nitro; or R2, R3, R4 and R5 are independently selected from hydrogen, lower alkyl, nitro, chloro, fluoro, methoxycarbonyl or methylcarbonyl, provided at least one is hydrogen, and R6 is hydrogen; or a pharmaceutically acceptable ester, ether or salt thereof.