74629-69-9

Upstream product

• 38239-55-3 4-hydroxychalcone 
• 137-07-5 2-amino-benzenethiol 
• 20426-12-4 (E)-3-(4-hydroxyphenyl)-1-phenyl-2-propen-1-one 

Downstream Products

• 125989-73-3 N-Phenyl-2-[4-(4-phenyl-2,3-dihydro-benzo[b][1,4]thiazepin-2-yl)-phenoxy]-acetamide 
• 125989-81-3 2-(4-Oxiranylmethoxy-phenyl)-4-phenyl-2,3-dihydro-benzo[b][1,4]thiazepine 
• 125989-71-1 2-[4-(4-Phenyl-2,3-dihydro-benzo[b][1,4]thiazepin-2-yl)-phenoxy]-acetamide 
• 125989-67-5 [4-(4-Phenyl-2,3-dihydro-benzo[b][1,4]thiazepin-2-yl)-phenoxy]-acetic acid 
• 74642-74-3 2,3-dihydro-2-<4-(tetra-O-acetyl-β-D-glucosyloxy)-phenyl>-4-phenyl-1,5-benzothiazepine 
• 125989-77-7 Methyl-carbamic acid 4-(4-phenyl-2,3-dihydro-benzo[b][1,4]thiazepin-2-yl)-phenyl ester 
• 125989-69-7 [4-(4-Phenyl-2,3-dihydro-benzo[b][1,4]thiazepin-2-yl)-phenoxy]-acetic acid ethyl ester 
• 125989-75-5 [4-(4-Phenyl-2,3-dihydro-benzo[b][1,4]thiazepin-2-yl)-phenoxy]-acetonitrile 
• 125989-79-9 Phenyl-carbamic acid 4-(4-phenyl-2,3-dihydro-benzo[b][1,4]thiazepin-2-yl)-phenyl ester 

Relevant academic research and scientific papers

Catalyst-free synthesis of 2,3-dihydro-1,5-benzothiazepines in a renewable and biodegradable reaction medium

A clean and efficient strategy for the synthesis of benzothiazepines from chalcone and ortho-aminothiophenol has been reported. Here, glycerol, a biodegradable and reusable promoting medium, has been utilized under acid, base or metal-free conditions. The

A practical synthesis of 2,3-dihydro-1,5-benzothiazepines

2,3-Dihydro-1,5-benzothiazepines have been obtained through a domino process involving a Michael addition of 2-aminothiophenols to chalcones, followed by in situ cyclization. Up to 98% chemical yields have been obtained at room temperature under essential

Solvent-free synthesis of 1,5-benzothiazepines and benzodiazepines on inorganic supports

1,5-Benzothiazepines and 1,5-benzodiazepines have been synthesized in solvent-free conditions from chalcones and o-aminothiophenol or o-phenylenediamine in the presence of inorganic support. Silica gel was found to be an effective support for the synthesi

Synthesis of 2,4-diaryl-1,5-berizodiazepines and 2,4-diaryl-2,3-dihydro-1,5-benzothiazepines

Various 2,4-disubstituted-1,5-benzodiazepines have been prepared by condensing 1,3-diones with o-phcnylencdiaminc, and 2,4-diaryl 2,3-dihydro-1,5-benzothiazepines have been prepared by condensing hydroxychalconc and o-aminothiophenol in boiling dry xylene

Syntheses and Spectral Studies of Some 2-(Substituted phenyl)-4-phenyl-1,5-benzothiazepines

2,3-Dihydro-2-(substituted phenyl)-4-phenyl-1,5-benzothiazepines (XI-XIX) have been synthesized in good yields by reacting chalkones (I-IX) with 2-aminobenzenethiol.The hydroxyl group at position 2 or 4 alone or along with other groups in ring-B has been