746622-11-7

Basic information

• Product Name: 3-(2-amino-5-methylphenyl)-1-propanol
• Synonyms: 3-(2-amino-5-methylphenyl)-1-propanol
• CAS NO: 746622-11-7
• Molecular Weight: 165.235
• Mol File: 746622-11-7.mol

Chemical Properties

• CAS DataBase Reference: 3-(2-amino-5-methylphenyl)-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-amino-5-methylphenyl)-1-propanol(746622-11-7)
• EPA Substance Registry System: 3-(2-amino-5-methylphenyl)-1-propanol(746622-11-7)

Safety Data

• Hazardous Substances Data: 746622-11-7(Hazardous Substances Data)

Upstream product

• 29289-13-2 2-iodo-4-methylaniline 

Downstream Products

• 20150-83-8 6-methyl-1,2,3,4-tetrahydroquinolin-2-one 

Relevant articles and documents

Synthesis of five-, six-, and seven-membered ring lactams by Cp*Rh complex-catalyzed oxidative N-heterocyclization of amino alcohols

A new effective catalytic system consisting of [Cp*RhCl 2]2/K2CO3 (Cp* = pentamethylcyclopentadienyl) for the lactamization of amino alcohols has been developed. As an example, the reaction of 3-(2-aminophenyl)-1-propanol in the presence of [Cp*RhCl2]2 (5.0% Rh) and K 2CO3 (10%) in acetone gives 3,4-dihydro-2(1H)-quinolinone in an isolated yield of 80%. A variety of five-, six-, and seven-membered benzo-fused lactams are synthesized by this catalytic system.