746668-59-7 Usage
Uses
Used in Pharmaceutical Industry:
6-BROMO-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new chemical entities. Its unique structure and reactivity play a crucial role in the creation of innovative drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 6-BROMO-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE is utilized as a building block in the synthesis of agrochemicals, such as pesticides and herbicides. Its reactivity and structural properties enable the development of effective compounds for agricultural applications, contributing to crop protection and yield enhancement.
Used in Material Science:
6-BROMO-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE is employed as a versatile intermediate in material science for its potential to contribute to the development of novel materials with unique properties. Its reactivity and structural characteristics make it suitable for use in the synthesis of advanced materials for various applications, including electronics, coatings, and polymers.
Used in Organic Synthesis:
As an important intermediate in organic synthesis, 6-BROMO-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE is used for the synthesis of a wide range of organic compounds. Its unique structure and reactivity allow for the creation of new chemical entities with potential applications in various industries, showcasing its versatility and importance in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 746668-59-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,6,6,6 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 746668-59:
(8*7)+(7*4)+(6*6)+(5*6)+(4*6)+(3*8)+(2*5)+(1*9)=217
217 % 10 = 7
So 746668-59-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H6BrN3/c1-5-6(8)2-3-7-9-4-10-11(5)7/h2-4H,1H3
746668-59-7Relevant academic research and scientific papers
2,3-DISUBSTITUTED PYRIDINE COMPOUNDS AS TGF-BETA INHIBITORS AND METHODS OF USE
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, (2015/11/27)
The invention described herein comprises compounds of formula (IV) and a method of treating cancer comprising administering to a subject having cancer one of the compounds in conjunction with another therapeutic treatment of cancer. The compounds (IV) inhibit signaling by a member of the TGF-β superfamily such as Nodal or Activin.
(2S,3S)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1, 2,4]triazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: A selective α-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Edmondson, Scott D.,Mastracchio, Anthony,Mathvink, Robert J.,He, Jiafang,Harper, Bart,Park, You-Jung,Beconi, Maria,Di Salvo, Jerry,Eiermann, George J.,He, Huaibing,Leiting, Barbara,Leone, Joseph F.,Levorse, Dorothy A.,Lyons, Kathryn,Patel, Reshma A.,Patel, Sangita B.,Petrov, Aleksandr,Scapin, Giovanna,Shang, Jackie,Roy, Ranabir Sinha,Smith, Aaron,Wu, Joseph K.,Xu, Shiyao,Zhu, Bing,Thornberry, Nancy A.,Weber, Ann E.
, p. 3614 - 3627 (2007/10/03)
A series of β-substituted biarylphenylalanine amides were synthesized and evaluated as inhibitors of dipeptidyl peptidase IV (DPP-4) for the treatment of type 2 diabetes. Optimization of the metabolic profile of early analogues led to the discovery of (2S
PYRAZOLES AND METHODS OF MAKING AND USING THE SAME
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Page 32, (2010/02/08)
The invention is based on the discovery that compounds of formula I possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of formula I (I).
