746673-85-8Relevant academic research and scientific papers
Optimization of the pharmacokinetic properties of potent anti-trypanosomal triazine derivatives
Salado, Irene G.,Baán, Adrienn,Verdeyen, Tomas,Matheeussen, An,Caljon, Guy,Van der Veken, Pieter,Kiekens, Filip,Maes, Louis,Augustyns, Koen
, p. 18 - 26 (2018)
Human African trypanosomiasis is causing thousands of deaths every year in the rural areas of sub-saharan Africa. There is a high unmet medical need since the approved drugs are poorly efficacious, show considerable toxicity and are not easy to administer
TANK-BINDING KINASE INHIBITOR COMPOUNDS
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Paragraph 0485, (2016/05/02)
Compounds having the following formula (I) and methods of their use and preparation are disclosed:
