Optimization of the pharmacokinetic properties of potent anti-trypanosomal triazine derivatives

DOI: 10.1016/j.ejmech.2018.03.048

Source and publish data:

European Journal of Medicinal Chemistry p. 18 - 26 (2018)

Update date:2022-07-30

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Authors:

Salado, Irene G.

Baán, Adrienn

Verdeyen, Tomas

Matheeussen, An

Caljon, Guy

Van der Veken, Pieter

Kiekens, Filip

Maes, Louis

Augustyns, Koen

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Article abstract of DOI:10.1016/j.ejmech.2018.03.048

Human African trypanosomiasis is causing thousands of deaths every year in the rural areas of sub-saharan Africa. There is a high unmet medical need since the approved drugs are poorly efficacious, show considerable toxicity and are not easy to administer

Full text of DOI:10.1016/j.ejmech.2018.03.048

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