74668-72-7

Basic information

• Product Name: CHEMBRDG-BB 5175101
• Synonyms: CHEMBRDG-BB 5175101;2-METHOXY-8-QUINOLINOL;2-methoxy-8-quinolinol(SALTDATA: FREE);2-METHOXY-8-HYDROXY QUINOLINE
• CAS NO: 74668-72-7
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.18
• Mol File: 74668-72-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 50.5 °C(Solv: hexane (110-54-3))
• Boiling Point: 324.4°C at 760 mmHg
• Flash Point: 150°C
• Appearance: /
• Density: 1.258g/cm³
• Vapor Pressure: 0.00013mmHg at 25°C
• Refractive Index: 1.649
• PKA: 10.27±0.10(Predicted)
• CAS DataBase Reference: CHEMBRDG-BB 5175101(CAS DataBase Reference)
• NIST Chemistry Reference: CHEMBRDG-BB 5175101(74668-72-7)
• EPA Substance Registry System: CHEMBRDG-BB 5175101(74668-72-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 74668-72-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H9NO2/c1-13-9-6-5-7-3-2-4-8(12)10(7)11-9/h2-6,12H,1H3

Upstream product

• 343788-51-2 8-(benzyloxy)-2-chloroquinoline 
• 63404-84-2 8-(benzyloxy)quinolin-2-ol 
• 15450-76-7 quinoline-2,8-diol 
• 642477-85-8 8-(benzyloxy)-2-methoxyquinoline 

Relevant articles and documents

PRMT5 INHIBITORS AND USES THEREOF

Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.

NOVEL COMPOUNDS HAVING AN ANTI-BACTERIAL ACTIVITY

The present invention describes novel anti-bacterial compounds of formula (I). These compounds are, amongst others, of interest as inhibitors of DNA gyrase.