74669-75-3

Basic information

• Product Name: (R)-3-Methyl-2-phenylbutylazid
• Synonyms: (R)-3-Methyl-2-phenylbutylazid
• CAS NO: 74669-75-3
• Molecular Weight: 189.26
• Mol File: 74669-75-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-3-Methyl-2-phenylbutylazid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-Methyl-2-phenylbutylazid(74669-75-3)
• EPA Substance Registry System: (R)-3-Methyl-2-phenylbutylazid(74669-75-3)

Safety Data

• Hazardous Substances Data: 74669-75-3(Hazardous Substances Data)

Upstream product

• 13491-13-9 (R)-2-isopropyl-2-phenylacetic acid 
• 586341-97-1 (3R,4E)-2-methyl-3-phenylhex-4-enoic acid 
• 586341-98-2 (3R,4E)-2-methyl-3-phenylhex-4-en-1-ol 
• 78019-45-1 (S)-(E)-4-Phenyl-5-methyl-2-hexene 
• 81176-43-4 (S)-trans-4-phenyl-3-buten-2-ol 
• 23406-60-2 (2R)-3-methyl-2-phenylbutan-1-ol 
• 67152-34-5 (R)-3-Methyl-2-phenylbutyltosylat 

Downstream Products

• 196106-01-1 (R)-3-methyl-2-phenylbutan-1-amine 

Relevant articles and documents

Enantioselective synthesis of benzylic stereocentres via Claisen rearrangement of enantiomerically pure allylic alcohols: Preparation of (R)- and (S)-3-methyl-2-phenylbutylamine

The Johnson-Claisen rearrangement of enantiopure allylic alcohols in triethylorthopropionate is the key step for the preparation of chiral molecules with benzylic stereogenic carbon atoms bearing an isopropyl moiety. The synthetic procedure is applied to the preparation of (R)- and (S)-3-methyl-2-phenylbutylamine.