7467-48-3 Usage
Uses
Used in Oncology:
4-AMINO-N-CYCLOHEXYL-N-METHYL-BENZENESULFONAMIDE is used as an antineoplastic agent for its ability to target and inhibit the enzyme carbonic anhydrase IX, which is overexpressed in various tumors. This action disrupts the pH balance of tumor cells, impairing their adaptation to hypoxic conditions and contributing to the inhibition of tumor growth and progression.
Used in Cancer Treatment:
In the field of cancer treatment, 4-AMINO-N-CYCLOHEXYL-N-METHYL-BENZENESULFONAMIDE is used as a potential therapeutic agent for the treatment of various cancers, including breast, lung, and pancreatic cancer. Its mechanism of action involves the inhibition of carbonic anhydrase IX, which is associated with tumor hypoxia, thereby affecting the tumor microenvironment and growth.
Used in Overcoming Chemotherapy Resistance:
4-AMINO-N-CYCLOHEXYL-N-METHYL-BENZENESULFONAMIDE is also being studied for its potential role in overcoming resistance to traditional chemotherapeutic agents. This application is based on its ability to target the hypoxic conditions within tumors, which are often associated with resistance to standard cancer treatments.
Further research is ongoing to investigate the safety and efficacy of 4-AMINO-N-CYCLOHEXYL-N-METHYL-BENZENESULFONAMIDE in human clinical trials, with the aim of expanding its applications in the medical field.
Check Digit Verification of cas no
The CAS Registry Mumber 7467-48-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,6 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 7467-48:
(6*7)+(5*4)+(4*6)+(3*7)+(2*4)+(1*8)=123
123 % 10 = 3
So 7467-48-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H20N2O2S/c1-15(12-5-3-2-4-6-12)18(16,17)13-9-7-11(14)8-10-13/h7-10,12H,2-6,14H2,1H3
7467-48-3Relevant academic research and scientific papers
Synthesis of n-mono-and n,n-disubstituted 4-aminobenzenesulfonamides
Mikhura,Formanovskii
, p. 64 - 68 (2007/10/03)
-N-Mono-and N,N-disubstituted 4-aminobenzenesulfonamides were synthesized by reaction of 4-acetylacetylaminobenzenesulfonyl chloride with the corresponding primary and secondary aliphatic and aromatic amines, followed by removal of the acetyl group via acid hydrolysis.
