74674-82-1

Upstream product

• 91-02-1 phenyl(pyridin-2-yl)methanone 
• 14474-59-0 naphthalen-1-yl-lithium 
• 694-59-7 pyridine N-oxide 
• 642-29-5 1-benzoylnaphthalene 
• 1443984-96-0 2-(naphthalen-1-yl(phenyl)methyl)pyridine 
• 1121-60-4 pyridine-2-carbaldehyde 
• 90-11-9 1-Bromonaphthalene 
• 113631-11-1 naphthalen-2-yl(pyridine-2-yl)methanol 

Relevant academic research and scientific papers

Iron-catalyzed C-H bond functionalization for the exclusive synthesis of pyrido[1,2-a]indoles or triarylmethanols

The efficient and selective iron-catalyzed C-H activation of 2-benzhydrylpyridine derivatives was employed for the preparation of pyrido[1,2-a]indoles through an intramolecular C-H amination reaction. In the presence of molecular oxygen as the sole oxidant, the same 2-benzhydrylpyridines were also used for the synthesis of the corresponding tertiary alcohols. In these approaches, the iron catalyst was used to selectively activate the C(sp2)-H bond of 2-benzhydrylpyridine, in the case of the intramolecular ring-closing C-H amination reaction in which the pyridine nitrogen atom was a directing group as well as a nucleophile, and the C(sp3)-H bond of the same compound, in the case of the oxidation reaction to give the corresponding triaryl carbinol.

DIARYLHYDROXYMETHYLATION OF PYRIDINE N-OXIDE BY THE RADICAL ANIONS OF SOME AROMATIC KETONES

In the reaction of the ketyls 4-phenylbenzophenone and phenyl 1-naphthyl ketone with pyridine N-oxide phenyl-4'-biphenylyl-2-pyridylcarbinol N-oxide, phenyl-4'-biphenylyl-2-pyridylcarbinol, phenyl-1'-naphthyl-2-pyridylcarbinol, and dimerization products (bipyridyls) vere obtained.The ketyl of phenyl 5-acenaphthenyl ketone does not form condensation products.In contrast to pyridine, pyridine N-oxide does not enter into the Emmert reaction.