74684-63-2

Basic information

• Product Name: threo-2-Azido-1,2-diphenylethanol
• Synonyms: threo-2-Azido-1,2-diphenylethanol
• CAS NO: 74684-63-2
• Molecular Weight: 239.277
• Mol File: 74684-63-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: threo-2-Azido-1,2-diphenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: threo-2-Azido-1,2-diphenylethanol(74684-63-2)
• EPA Substance Registry System: threo-2-Azido-1,2-diphenylethanol(74684-63-2)

Safety Data

• Hazardous Substances Data: 74684-63-2(Hazardous Substances Data)

Upstream product

• 645-49-8 cis-stilben 
• 1439-07-2 trans-Stilbene oxide 
• 1689-71-0 cis-1,2-diphenyloxirane 

Downstream Products

• 74684-64-3 <((1R*,2R*)-2-Hydroxy-1,2-diphenylaethyl)amido>phosphorsaeure-diaethylester 
• 1643952-50-4 cis-1-(2,4-dinitrobenzoyl)-2,3-diphenylaziridine 
• 1643952-64-0 2-(2,4-dinitrobenzamido)-1,2-diphenylethyl benzoate 
• 1605-06-7 cis-2,3-diphenylaziridine 
• 25125-72-8 trans-2,2-Diphenylaziridine 

Relevant articles and documents

HIGHLY REGIO AND CHEMOSELECTIVE RING OPENING OF EPOXIDES WITH TRIMETHYLSILYL AZIDE IN THE PRESENCE OF ALUMINIUM ISOPROPOXIDE AND TITANIUM ISOPROPOXIDE

The ring-opening of functionalized epoxides with trimethylsilyl azide in the presence of a catalytic amount of Ti(O-i-Pr)4 or Al(O-i-Pr)3 is described.The reaction is stereospecific and highly regiospecific, leading generally to the formation of the carbon-azido bond on the less substituted carbon.The mechanism of this reaction is also discussed.

Bronsted acid-catalyzed desymmetrization of meso-aziridines

The enantioselective ring-opening of meso-aziridines with azide nucleophiles proceeded in the presence of a catalytic amount of a chiral phosphoric acid catalyst. The reaction affords the formation of the products in excellent yield and enantioselectivity. Preliminary mechanistic studies indicate that the active catalytic species is a chiral silane that is generated in situ. Copyright