74719-00-9Relevant academic research and scientific papers
Iridium(i)-catalyzed hydration/esterification of 2-alkynylphenols and carboxylic acids
Zeng, Linwei,Chen, Renjie,Zhang, Chen,Xie, Hujun,Cui, Sunliang
, p. 3093 - 3096 (2020)
An iridium(i)-catalyzed hydration/esterification of 2-alkynylphenols and carboxylic acids is described. Various 2-alkynylphenols and carboxylic acids could be used in this process to furnish aromatic ortho-acyloxyketones via a regio- and stereo-selective addition reaction followed by intramolecular rearrangement. This protocol features mild reaction conditions and broad substrate scope. Further transformations were conducted to demonstrate the synthetic application.
