7472-96-0

Basic information

• Product Name: 3-(2-methoxyphenyl)-2-benzofuran-1(3H)-one
• CAS NO: 7472-96-0
• Molecular Formula: C₁₅H₁₂O₃
• Molecular Weight: 240.254
• Mol File: 7472-96-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 391.5°C at 760 mmHg
• Flash Point: 165.1°C
• Density: 1.236g/cm³
• Vapor Pressure: 2.44E-06mmHg at 25°C
• Refractive Index: 1.602
• CAS DataBase Reference: 3-(2-methoxyphenyl)-2-benzofuran-1(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-methoxyphenyl)-2-benzofuran-1(3H)-one(7472-96-0)
• EPA Substance Registry System: 3-(2-methoxyphenyl)-2-benzofuran-1(3H)-one(7472-96-0)

Safety Data

• Hazardous Substances Data: 7472-96-0(Hazardous Substances Data)

Upstream product

• 610-94-6 2-bromobenzoic acid methyl ester 
• 135-02-4 ortho-anisaldehyde 
• 57271-91-7 N-butyl-2-hydroxybenzamide 
• 119-36-8 methyl salicylate 
• 5720-06-9 2-Methoxyphenylboronic acid 
• 119-67-5 o-carboxybenzaldehyde 
• 84761-77-3 2-formylphenyl triflate 
• 4122-56-9 methyl o-formylbenzoate 
• 16750-63-3 2-methoxyphenylmagnesium bromide 
• 7468-67-9 o-formylbenzonitrile 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 86911-84-4 4-Hydroxy-4-(2-methoxy-phenyl)-but-2-ynoic acid ethyl ester 
• 1165952-91-9 cyclohexa-1,3-diene 

Downstream Products

• 1151-04-8 2-(2-methoxybenzoyl)benzoic acid 

Relevant articles and documents

Access to Diarylmethanols by Wittig Rearrangement of ortho-, meta-, and para-Benzyloxy- N-Butylbenzamides

The N-butyl amide group, CONHBu, has been found to be an effective promoter of the [1,2]-Wittig rearrangement of aryl benzyl ethers and thus allow the two-step synthesis of isomerically pure substituted diarylmethanols starting from simple hydroxybenzoic acid derivatives. The method is compatible with a wide range of functional groups including methyl, methoxy, and fluoro, although not with nitro and, unexpectedly, is applicable to meta as well as ortho and para isomeric series.

Direct and selective synthesis of 3-arylphthalides via nickel-catalyzed aryl addition/intramolecular esterification

Herein we report a nickel-catalyzed aryl addition/intramolecular esterification in a cascade fashion. Under the combination of commercially available nickel precursor and tridentate ligand, the one pot protocol offers a direct, simple and regioselective approach to access 3-aryl phthalide derivatives from two readily available substrates with good efficiency, broad scope as well as satisfactory functional group compatibility.

Rhodium or palladium-catalyzed cascade aryl addition/intramolecular lactonization of phthalaldehydonitrile to access 3-aryl and 3-alkenyl phthalides

A rhodium or palladium-catalyzed addition of boronic acids to phthalaldehydonitrile, followed by an intramolecular lactonization of cyano to access 3-substituted phthalides, is described. This procedure tolerates a series of functional groups, such as methoxy, fluoro, chloro, and vinyl groups. It is a novel procedure for the synthesis of 3-arylphthalides.