74733-90-7

Usage

Uses

Used in Organic Synthesis:
2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole serves as a valuable building block in organic synthesis, contributing to the creation of a wide range of chemical compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole is utilized for the synthesis of pharmaceuticals, potentially leading to the development of new drugs with various therapeutic applications.
Used in Agrochemicals:
2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole also finds application in the synthesis of agrochemicals, playing a role in the development of pesticides and other agricultural products to enhance crop protection and yield.
Used in Materials Science:
2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole has potential applications in materials science, where it can be incorporated into the design and synthesis of new materials with specific properties for various industrial uses.
Used in Anti-Cancer Research:
2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole is being studied for its anti-cancer properties, with the potential to contribute to the development of novel therapeutic agents for the treatment of cancer.
Used in Anti-Fungal Research:
Additionally, 2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole is explored for its anti-fungal properties, which may lead to the creation of new anti-fungal agents to combat fungal infections.

Upstream product

• 51039-49-7 2-phenyl-2H-[1,2,3]triazole 
• 29841-71-2 (1E,2E)-1,2-bis(2-phenylhydrazono)ethane 
• 100-63-0 phenylhydrazine 
• 622-88-8 4-bromophenylhydrazine hydrochloride 
• 74741-27-8 glyoxal bis-(p-bromophenyl)hydrazone 
• 74733-89-4 1,2-bis-(p-bromophenylazo)ethylene 

Downstream Products

• 126554-09-4 2-(4-bromo-2-nitrophenyl)-4-nitro-1,2,3-triazole 
• 1398503-39-3 (2R)-4-{5-fluoro-2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl}-2-methyl-2-(methylsulfonyl)-N-(tetrahydro-2H-pyran-2-yloxy)butanamide 
• 1398501-95-5 (2R)-4-{5-fluoro-2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl}-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide 
• 1398503-38-2 (2R)-4-{5-fluoro-2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl}-2-methyl-2-(methylsulfonyl)butanoic acid 
• 1398503-37-1 ethyl (2R)-4-{5-fluoro-2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl}-2-methyl-2-(methylsulfonyl)butanoate 
• 1312479-18-7 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2H-1,2,3-triazole 
• 1312473-81-6 (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-{2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl}butanamide 
• 1312479-19-8 (2R)-2-methyl-2-(methylsulfonyl)-4-{2-oxo-4-[4-(2H-1,2,3-triazol-2-yl)phenyl]pyridin-1(2H)-yl}-N-(tetrahydro-2H-pyran-2-yloxy)butanamide 

Relevant academic research and scientific papers

Synthesis of 2-Substituted 1,2,3-Triazoles via an Intramolecular N–N Bond Formation

An efficient synthesis of 2-aryl 1,2,3-triazoles based on an intramolecular N–N bond formation is described. Selective activation of bis-hydrazone at the dimethylamino hydrazone group with MeI forms a mono-hydrazonium species. Treatment of the hydrazonium

HYDROXAMIC ACID DERIVATIVES AS LPXC INHIBITORS FOR THE TREATMENT OF BACTERIAL INFECTIONS

This invention pertains generally to antibacterial organic compounds of Formula I as described herein, and pharmaceutical compositions containing such compounds. In certain aspects, the invention pertains to treating infections caused by Gram-negative bac

SYNTHESIS OF 4-NITRO-1,2,3-TRIAZOLES

Preparative methods were studied for the synthesis of 4-nitro-1,2,3-triazole and its N-oxide by the nitration of 2-phenyl-substituted triazoles followed by elimination of the nitrophenyl fragment, which can be successfully removed when it contains two nitro groups.

Isomerism and Lead(IV) Acetate Oxidation Reactions of p-Substituted Phenylosazones of Some Substituted Glyoxals and 1,2-Diketones. Reactions of Metallic Acetates with Nitrogen Compounds. Part 5.

The structures of the bis-(p-nitrophenyl)hydrazones and some bis-(p-bromophenyl)hydrazones of glyoxal, methylglyoxal, phenylglyoxal, butane-2,3-dione, benzil, and cyclohexane-1,2-dione were examined by i.r., 1H n.m.r., and 13C n.m.r. spectroscopy.Generally the E,E forms of the osazones were obtained from direct synthesis except for the bis-(p-nitrophenyl)hydrazone of cyclohexane-1,2-dione and phenylglyoxal and the bis-(p-bromophenyl)hydrazones of phenylglyoxal, which were obtained as the E,Z-chelate forms.Unstable yellow crystalline forms of the bis-(p-nitrophenyl)hydrazones of glyoxal, butane-2,3-dione, and benzil containing two molecules of hexamethylphosphoramide (HMPA) of crystallisation, which may contain the E,Z-isomers, were isolated from HMPA solutions.Lead tetra-acetate oxidation of a range of E,E-osazones gave dehydrogenations to 1,2-bisazoethylenes.Similar oxidations of E,Z-osazones gave mainly 2-aryl-1,2,3-trizole type products (osotriazoles) along with lower yields of azoethylenes.Oxidation of cyclohexane-1,2-dione bis-(p-nitrophenyl)hydrazone gave a mixture of osotriazoles containing an acethoxy- or p-nitroacetanilido-group at the 3-position of the cyclohexyl ring.