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2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole, also known as 4-Bromo-1-phenyl-1H-1,2,3-triazole, is a heterocyclic chemical compound with the molecular formula C9H6BrN3. It features a five-membered triazole ring consisting of two carbon atoms and three nitrogen atoms, with a bromine atom attached to a phenyl group. This white to off-white solid is soluble in organic solvents such as acetone, ethanol, and dichloromethane.

74733-90-7

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74733-90-7 Usage

Uses

Used in Organic Synthesis:
2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole serves as a valuable building block in organic synthesis, contributing to the creation of a wide range of chemical compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole is utilized for the synthesis of pharmaceuticals, potentially leading to the development of new drugs with various therapeutic applications.
Used in Agrochemicals:
2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole also finds application in the synthesis of agrochemicals, playing a role in the development of pesticides and other agricultural products to enhance crop protection and yield.
Used in Materials Science:
2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole has potential applications in materials science, where it can be incorporated into the design and synthesis of new materials with specific properties for various industrial uses.
Used in Anti-Cancer Research:
2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole is being studied for its anti-cancer properties, with the potential to contribute to the development of novel therapeutic agents for the treatment of cancer.
Used in Anti-Fungal Research:
Additionally, 2-(4-Bromo-Phenyl)-2H-[1,2,3]Triazole is explored for its anti-fungal properties, which may lead to the creation of new anti-fungal agents to combat fungal infections.

Check Digit Verification of cas no

The CAS Registry Mumber 74733-90-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,7,3 and 3 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 74733-90:
(7*7)+(6*4)+(5*7)+(4*3)+(3*3)+(2*9)+(1*0)=147
147 % 10 = 7
So 74733-90-7 is a valid CAS Registry Number.

74733-90-7Relevant academic research and scientific papers

Synthesis of 2-Substituted 1,2,3-Triazoles via an Intramolecular N–N Bond Formation

Chen, Cheng-yi,Lu, Xiaowei,Holland, Mareike C.,Lv, Shichang,Ji, Xuebao,Liu, Wei,Liu, Jie,Depre, Dominique,Westerduin, Pieter

, p. 548 - 551 (2019/12/24)

An efficient synthesis of 2-aryl 1,2,3-triazoles based on an intramolecular N–N bond formation is described. Selective activation of bis-hydrazone at the dimethylamino hydrazone group with MeI forms a mono-hydrazonium species. Treatment of the hydrazonium

HYDROXAMIC ACID DERIVATIVES AS LPXC INHIBITORS FOR THE TREATMENT OF BACTERIAL INFECTIONS

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Page/Page column 77, (2014/10/15)

This invention pertains generally to antibacterial organic compounds of Formula I as described herein, and pharmaceutical compositions containing such compounds. In certain aspects, the invention pertains to treating infections caused by Gram-negative bac

SYNTHESIS OF 4-NITRO-1,2,3-TRIAZOLES

Vereshchagin, L. I.,Nikitin, V. M.,Meshcheryakov, V. I.,Gareev, G. A.,Kirillova, L. P.,Shul'gina, V. M.

, p. 1574 - 1577 (2007/10/02)

Preparative methods were studied for the synthesis of 4-nitro-1,2,3-triazole and its N-oxide by the nitration of 2-phenyl-substituted triazoles followed by elimination of the nitrophenyl fragment, which can be successfully removed when it contains two nitro groups.

Isomerism and Lead(IV) Acetate Oxidation Reactions of p-Substituted Phenylosazones of Some Substituted Glyoxals and 1,2-Diketones. Reactions of Metallic Acetates with Nitrogen Compounds. Part 5.

Butler, Richard N.,Cunningham, Michael G.

, p. 744 - 749 (2007/10/02)

The structures of the bis-(p-nitrophenyl)hydrazones and some bis-(p-bromophenyl)hydrazones of glyoxal, methylglyoxal, phenylglyoxal, butane-2,3-dione, benzil, and cyclohexane-1,2-dione were examined by i.r., 1H n.m.r., and 13C n.m.r. spectroscopy.Generally the E,E forms of the osazones were obtained from direct synthesis except for the bis-(p-nitrophenyl)hydrazone of cyclohexane-1,2-dione and phenylglyoxal and the bis-(p-bromophenyl)hydrazones of phenylglyoxal, which were obtained as the E,Z-chelate forms.Unstable yellow crystalline forms of the bis-(p-nitrophenyl)hydrazones of glyoxal, butane-2,3-dione, and benzil containing two molecules of hexamethylphosphoramide (HMPA) of crystallisation, which may contain the E,Z-isomers, were isolated from HMPA solutions.Lead tetra-acetate oxidation of a range of E,E-osazones gave dehydrogenations to 1,2-bisazoethylenes.Similar oxidations of E,Z-osazones gave mainly 2-aryl-1,2,3-trizole type products (osotriazoles) along with lower yields of azoethylenes.Oxidation of cyclohexane-1,2-dione bis-(p-nitrophenyl)hydrazone gave a mixture of osotriazoles containing an acethoxy- or p-nitroacetanilido-group at the 3-position of the cyclohexyl ring.

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