7474-84-2Relevant articles and documents
Research on antitumor chemotherapy: X. β Nitrostyrene and nitrovinyl derivatives
Dore,Viel
, p. 81 - 109 (2007/10/06)
In previous work, the antitumoral cytotoxicity of β nitrostyrenes obtained by simplification of the aristolochic acid molecule was demonstrated. The effect of modifying the 3 characteristic parts of the β nitrostyrene molecule was then investigated. Results in vitro and in vivo indicate a probable mechanism of action for the β nitrostyrene and nitrovinyl compounds studied, and permit definition of the maximum simplification compatible with retention of biological activity.