74741-10-9Relevant academic research and scientific papers
vic-Iodothiocyanates and Iodoisothiocyanates. Part 3. Further Preperations, and the Formation of 2-Alkoxy-2-thiazolines
Cambie, Richard C.,Chambers, David,Rutledge, Peter S.,Woodgate, Paul D.,Woodgate, Shella D.
, p. 33 - 39 (2007/10/02)
The reactions of (E)-hex-3-ene, 4-t-butylcyclohexene, and 3-t-butylcyclohexene with iodine and potassium thiocyanate are examined.The action of iodine and thiocyanogen with (E)-hex-3-ene gives different results from those reported in the literature.Isomerization of the vic-iodothiocyatates and formation of 2-alkoxy-2-thiazolines from the latter adducts are reported.
Oxidative Displacement of Hypervalent Iodine from Alkyl Iodides
Cambie, Richard C.,Chambers, David,Lindsay, Barry G.,Rutledge, Peter S.,Woodgate, Paul D.
, p. 822 - 827 (2007/10/02)
Oxidative displacement of iodine from primary alkyl iodides and vic-substituted iodocyclohexanes with m-chloroperbenzoic acid in either dichloromethane or t-butyl alcohol-water gives primary alcohols and vic-substituted cyclohexanols, respectively.Retention of configuration at the displacement centre occurs for all of the trans-vic-substituted iodocyclohexanes except the iodoacetate and iodotrifluoroacetate where inversion of configuration occurs to give cis-hydroxy-esters.Oxidation of (S)-2-iodo-octane occurs with almost complete inversion to give (R)-octan-2-ol but also affords octan-1-ol, octan-3-ol, and octan-2-one.
