74745-35-0

Upstream product

• 74745-26-9 8-Hydroxy-3-methoxy-1-phenyl-5,6,7,8-tetrahydro-isoquinoline-4-carbonitrile 
• 3580-38-9 2-Benzoylcyclohexanone 
• 74745-18-9 3-Methoxy-8-oxo-1-phenyl-5,6,7,8-tetrahydro-isoquinoline-4-carbonitrile 
• 74745-10-1 3-Methoxy-1-phenyl-5,6,7,8-tetrahydro-isoquinoline-4-carbonitrile 
• 53661-29-3 3-hydroxy-1-phenyl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile 

Downstream Products

• 74745-48-5 3-Methoxy-1-phenyl-isoquinoline-4-carbonitrile 
• 74745-44-1 3-Methoxy-1-phenyl-1,2-dihydro-isoquinoline-4-carbonitrile 

Relevant academic research and scientific papers

Amide-Catalysed Isomerisation of 5,6-Dihydroisoquinolines: a Novel Synthesis of 1,2-Dihydroisoquinolines

Knoevenagel condensation of 2-acylcyclohexanones or 2-ethoxycarbonylcyclohexanone with either cyanoacetamide or malononitrile followed by silver salt alkylation gave the 5,6,7,8-tetrahydroisoquinolines (3a-i).Chromic acid oxidation of the 5,6,7,8-tetrahyd

AMIDE CATALYSED FACILE ISOMERIZATION OF 5,6-DIHYDROISOQUINOLINES: SYNTHESIS OF STABLE 1,2-DIHYDROISOQUINOLINES.

Stable 1,2-dihydroisoquinolines have been synthesized by an amide catalysed novel isomerization reaction of 5,6-dihyroisoquinolines.