74756-09-5

Basic information

• Product Name: (1S,2S,4R)-4-Isopropenyl-1-methyl-2-phenylselanyl-cyclohexanol
• Synonyms: (1S,2S,4R)-4-Isopropenyl-1-methyl-2-phenylselanyl-cyclohexanol
• CAS NO: 74756-09-5
• Molecular Weight: 309.31
• Mol File: 74756-09-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (1S,2S,4R)-4-Isopropenyl-1-methyl-2-phenylselanyl-cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S,4R)-4-Isopropenyl-1-methyl-2-phenylselanyl-cyclohexanol(74756-09-5)
• EPA Substance Registry System: (1S,2S,4R)-4-Isopropenyl-1-methyl-2-phenylselanyl-cyclohexanol(74756-09-5)

Safety Data

• Hazardous Substances Data: 74756-09-5(Hazardous Substances Data)

Upstream product

• 1195-92-2 Limonene oxide 
• 1666-13-3 diphenyl diselenide 
• 14971-39-2 benzeneselenolate ion 
• 138-86-3 limonene. 
• 76338-32-4 Acetic acid (1R,2S,4S)-4-isopropenyl-1-methyl-2-phenylselanyl-cyclohexyl ester 
• 76338-31-3 6-acetoxy-2-hydroxy-2,6-dimethyl-3-phenylseleno-octa-7-ene 
• 6909-30-4 (1S,2R,4R)-limonene-1,2-epoxide 
• 5989-27-5 D-limonene 
• 1195-92-2 (4R)-limonene 1,2-epoxide 
• 115-95-7 linalool acetate 
• 41610-76-8 1-(3,4-epoxy-4-methylpentyl)-1-methylallyl acetate 

Downstream Products

• 74756-11-9 (1S,2S,4R)-2-phenylseleninyl-p-menth-8-en-1-ol 
• 22972-51-6 (1S,4R)-p-mentha-2,8-dien-1-ol 
• 68754-14-3 1-acetoxy-trans-p-mentha-2,8-diene 
• 3886-78-0 trans-p-mentha-2,8-dien-1-ol 

Relevant articles and documents

Preparation method of (1S, 4R)-1-methyl-4-(1-methyl vinyl)-2-cyclohexene-1-alcohol

The invention discloses a preparation method of (1S, 4R)-1-methyl-4-(1-methyl vinyl)-2-cyclohexene-1-alcohol, which comprises the following steps: by using D-limonene as a raw material, carrying out double bond addition and hydroxyl protection to obtain an intermediate compound; and carrying out elimination reaction and continuing deprotection to finally prepare the product. The method has the advantages of two-step continuous reaction, short process route and few byproducts, the obtained product has high chiral selectivity, and the yield is up to 70% or above and is greatly improved comparedwith the existing process.

Stereoselective Cyclization assisted by the Selenyl Group. Biogenetic-type Synthesis in the p-Menthane Series

Acid-catalysed cyclization of the β-hydroxyselenide (3), derived from linalyl acetate (1), afforded the trans-p-menthanes (4) and (5), the structures of which were confirmed by their transformation into (6), (11), (8), and (13), and alternative syntheses of these compounds.The structure determination of some products obtained by the reaction of limonene and α-terpineol epoxides with phenylselenium anion was also carried out.

Conversion of (+)-(R)-limonene into (+)-(1S,4R)-p-mentha-2,8-dien-1-ol, an intermediate in the synthesis of tetrahydrocannabinoids

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