74773-24-3

Upstream product

• 85010-70-4 5-(4-Cyclohexylmethoxy-benzyl)-2-imino-thiazolidin-4-one 
• 100-49-2 cyclohexylmethyl alcohol 
• 514196-20-4 5-(4-(cyclohexylmethoxy)benzylidene)thiazolidine-2,4-dione 
• 350-46-9 4-Fluoronitrobenzene 
• 85003-36-7 2-Chloro-3-(4-cyclohexylmethoxy-phenyl)-propionic acid methyl ester 
• 76253-40-2 1-Cyclohexylmethoxy-4-nitro-benzene 
• 76253-28-6 4-(cyclohexylmethoxy)aniline 
• 126521-53-7 4-(cyclohexylmethoxy)benzaldehyde 
• 459-57-4 4-fluorobenzaldehyde 

Relevant academic research and scientific papers

Composition for Distructing Microalgae

The present invention relates to a composition for disrupting microalgae. The composition for disrupting microalgae can suppress growth and proliferation of microalgae when treated in marine microalgae culture farms, areas where green or red tide takes pl

NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF

The present invention relates to novel thiazolidinedione derivatives expressed by the following formula (I) and the uses thereof. More specifically, the present invention relates to novel thiazolidinedione derivatives expressed by the following formula (I) and a pharmaceutical composition comprising the same. The novel thiazolidinedione derivatives of formula (I) according to the present invention can be effectively used for the prevention or treatment of cardiovascular disease, gastrointestinal disease and renal disease by inhibiting the activity of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) that decomposes prostaglandins as well as useful for the prevention of hair loss and the stimulation of hair growth, and osteogenic stimulation and wound healing.

Structure-activity requirements for the antiproliferative effect of troglitazone derivatives mediated by depletion of intracellular calcium

Depletion of calcium from the endoplasmic reticulum has shown to affect protein synthesis and cell proliferation. The anticancer effect of troglitazone was reported to be mediated by depletion of intracellular calcium stores resulting in inhibition of translation initiation. The unsaturated form of troglitazone displays similar anticancer properties in vitro. In this letter, we report our findings on the minimum structural requirements for both compounds to retain their calcium release and antiproliferative activities.