74794-87-9Relevant academic research and scientific papers
Dimethoxyindoles based thiosemicarbazones as multi-target agents; synthesis, crystal interactions, biological activity and molecular modeling
Bingul, Murat,Boga, Mehmet,Kandemir, Hakan,Koca, Mehmet Serdar,Saglam, Mehmet F.,Sengul, Ibrahim F.,Temel, Mutesir,Zorlu, Yunus,Y?ld?z, Minhal
, (2022/02/03)
Alzheimer's disease (AD) is known as one of the most devastating neurodegenerative disease diagnosed for the old-aged people and cholinesterase inhibitors (ChEI) can be used as an effective palliative treatment for AD. A range of novel monomeric and dimer
Iodine-mediated one-pot synthesis of indoles and 3-dimethylaminoindoles via annulation of enaminones
Jerezano, Alberto V.,Labarrios, Ehecatl M.,Jimenez, Fabiola E.,Del Cruz, Maria Carmen,Pazos, Diana C.,Gutierrez, Rsuini U.,Delgado, Francisco,Tamariz, Joaquin
, p. 18 - 53 (2014/03/21)
The synthesis of 2-carbonylindoles was achieved via a iodine-mediated cyclization of the corresponding enaminone precursors, which were formed by reaction of the ?-arylaminomethylene carbonyl derivatives with N,N'-dimethylformamide dimethyl acetal (DMFDMA). An alternative and more efficient procedure consisted of a similar cyclization of the enaminones, but under solvent-free and grinding reaction conditions. In another iodine-promoted procedure, 2-carbonyl-3-dimethylaminoindoles were synthesized via a one-pot cascade reaction between the α-arylaminomethylene carbonyl derivative and DMFDMA.ARKAT-USA, Inc.
Streptonigrin and related compounds. 6. Synthesis and activity of some quinoxaline analogues
Rao, Koppaka V.,Rock, Charles P.
, p. 447 - 458 (2007/10/03)
Streptonigrin is an antitumor antibiotic with significant in vitro and in vivo antitumor activity spectrum. Besides the total syntheses, numerous syntheses of the partial structures have been carried out in order to assess the structural requirements for
Investigation of the Bischler Indole Synthesis from 3,5-Dimethoxyaniline
Black, David St.C.,Gatehouse, Bryan M.K.C.,Theobald, Francois,Wong, Laurence C.H.
, p. 343 - 350 (2007/10/02)
Cyclization of the amino ketones (3a,b) derived from 3,5-dimethoxyaniline, and phenacyl bromide and 4-bromophenacyl bromide respectively, afforded 2-arylindoles (8a,b) in preference to 3-arylindoles (7).The 3-(4'bromophenyl)indole (7b) was also isolated i
