74802-14-5

Basic information

• Product Name: t-butyloxycarbonyl-L-kynurenylglycyl-L-phenylalanine 2,4,6-trimethylbenzyl ester
• Synonyms: t-butyloxycarbonyl-L-kynurenylglycyl-L-phenylalanine 2,4,6-trimethylbenzyl ester
• CAS NO: 74802-14-5
• Molecular Weight: 644.768
• Mol File: 74802-14-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: t-butyloxycarbonyl-L-kynurenylglycyl-L-phenylalanine 2,4,6-trimethylbenzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: t-butyloxycarbonyl-L-kynurenylglycyl-L-phenylalanine 2,4,6-trimethylbenzyl ester(74802-14-5)
• EPA Substance Registry System: t-butyloxycarbonyl-L-kynurenylglycyl-L-phenylalanine 2,4,6-trimethylbenzyl ester(74802-14-5)

Safety Data

• Hazardous Substances Data: 74802-14-5(Hazardous Substances Data)

Upstream product

• 18635-59-1 Phe-OTmb*HCl 
• 74802-13-4 t-butyloxycarbonyl-L-kynurenylglycine p-nitrophenyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 2922-83-0 L-kynurenine 
• 16055-80-4 (S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid sulfate 
• 74802-08-7 N^α-t-butyloxycarbonyl-L-kynurenine 

Downstream Products

• 74802-15-6 L-kynurenylglycyl-L-phenylalanine 

Relevant articles and documents

Syntheses of L-Kynurenine Peptides Conducted Without Masking the Side-Chain Amino Group

Various free L-kynurenine peptides, including an analogue of the opiate agonist leucine-enkephalin, have been synthesized by using the Nα-t-butoxycarbonyl derivative of L-kynurenine as a key precursor.By selecting appropriate mild conventional coupling procedures it was possible to carry out the synthetic operations without having to mask the side-chain amino group in any way, but intramolecular acylation with formation of a seven-membered lactam could be demonstrated under more vigorous conditions.