74807-93-5

Upstream product

• 74807-89-9 (2S)-Methoxymethyl-N-(2-propynyl)-1-pyrrolidinemethanimine 
• 100-39-0 benzyl bromide 
• 74807-90-2 (2S)-2-Methoxymethyl-N-(3-trimethylsilyl-2-propynyl)-1-pyrrolidinemethanimine 

Downstream Products

• 172358-32-6 4-Phenyl-1-butyn-3-amine 
• 74808-04-1 1-Methyl-4-phenyl-1-butyn-3-amine 
• 88224-45-7 1-Methyl-4-phenyl-1-trimethylsilyl-1-butyn-3-amine 
• 74807-96-8 (2S)-N-(1-Benzyl-1-methyl-3-trimethylsilyl-2-propynyl)-2-methoxymethyl-1-pyrrolidinemethanimine 
• 74808-02-9 (S)-1-Benzyl-1-methyl-prop-2-ynylamine 
• 30990-90-0 (S)-α-methyl-phenylalanine hydrochloride 
• 14603-77-1 (R)-α-methyl-phenylalanine hydrochloride 
• 74808-00-7 (S)-1-phenylbut-3-yn-2-amine 
• 88224-41-3 4-Phenyl-1-trimethylsilyl-1-butyn-3-amine 

Relevant academic research and scientific papers

Asymmetric Synthesis of α-Substituted Amino Acids and Amines by Carbon-Carbon Bond Formation in Position α to the Nitrogen

The asymmetric synthesis of α-substituted α-amino acids and propargylamines is described.As chiral auxiliary we used (S)-(-)-1-dimethoxymethyl-2-methoxymethylpyrrolidine (SDMP, 1).Treatment of the amino acids or amines with SDMP 1 afforded the correspondi