7484-37-9

Basic information

• Product Name: 3-PHENYLPROPYL TRIPHENYLPHOSPHONIUM BROMIDE
• Synonyms: 3-PHENYLPROPYL TRIPHENYLPHOSPHONIUM BROMIDE
• CAS NO: 7484-37-9
• Molecular Formula: Br*C₂₇H₂₆P
• Molecular Weight: 461.37
• EINECS: 231-289-3
• Mol File: 7484-37-9.mol
• Article Data: 24

Chemical Properties

• Melting Point: 209°C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• Sensitive: Hygroscopic
• BRN: 4173336
• CAS DataBase Reference: 3-PHENYLPROPYL TRIPHENYLPHOSPHONIUM BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PHENYLPROPYL TRIPHENYLPHOSPHONIUM BROMIDE(7484-37-9)
• EPA Substance Registry System: 3-PHENYLPROPYL TRIPHENYLPHOSPHONIUM BROMIDE(7484-37-9)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 7484-37-9(Hazardous Substances Data)

Usage

General Description

3-Phenylpropyl triphenylphosphonium bromide is a chemical compound used as a reactant in organic synthesis and as a catalyst in various chemical reactions. It is an organic salt with the chemical formula C21H21PBr, and it is typically a white or off-white solid. 3-PHENYLPROPYL TRIPHENYLPHOSPHONIUM BROMIDE is known for its strong lipid solubility, which makes it useful in membrane potential measurements and studies related to mitochondrial function. Additionally, it has been used in studies of the permeability and transport of ions and molecules across biological membranes. The compound is also known for its antimicrobial and antifungal properties, and it has been investigated for potential applications as a pharmaceutical agent. Overall, 3-Phenylpropyl triphenylphosphonium bromide is a versatile compound with a range of potential uses in organic chemistry, biochemistry, and medicinal chemistry.

InChI:InChI=1/C27H26P/c1-5-14-24(15-6-1)16-13-23-28(25-17-7-2-8-18-25,26-19-9-3-10-20-26)27-21-11-4-12-22-27/h1-12,14-15,17-22H,13,16,23H2/q+1

Upstream product

• 637-59-2 1-Bromo-3-phenylpropane 
• 603-35-0 triphenylphosphine 

Downstream Products

• 19871-06-8 2-(D₃)Methyl-5-phenyl-(1,1,1-D₃)penten-⁽²⁾ 
• 5717-40-8 Triphenylphosphin-(3-phenyl-1-aethoxycarbonyl-propylid) 
• 81276-67-7 1'-methyl-2,3-bis(2-phenylethyl)spiroindol>-2'(1'H)-one 
• 69485-56-9 pent-2-ene-1,5-diyldibenzene 
• 39110-26-4 (triphenylphosphonio)-3-phenyl-1-propanide 
• 146009-59-8 (1S,3S,4S,5R,6R,7R)-6-((E)-(4S,6S)-4,6-Dimethyl-oct-2-enoyloxy)-4-hydroxy-7-(1-methoxy-1-methyl-ethoxy)-1-((E)-6-phenyl-hex-3-enyl)-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid tri-tert-butyl ester 
• 52772-44-8 (Z)-1,6-diphenyl-3-hexene 
• 136559-12-1 2-methyl-6-phenyl-1,3-hexadiene 
• 152127-23-6 1-Benzyl-4-(3-phenylpropylidene)piperidine 
• 532399-77-2 2-((E)-4-Phenyl-but-1-enyl)-benzofuran-4-carboxylic acid ethyl ester 
• 5407-91-0 1,4-diphenylbutan-1-one 
• 126314-18-9 4-phenyl-1-(p-chlorophenyl)-1-butanone 
• 851592-02-4 (4R)-2,2-dimethyl-4-[(1Z)-4-phenylbut-1-enyl]-1,3-dioxolane 
• 886971-60-4 2-benzyl-1-[(tert-butyldimethylsilyl)oxy]-6-phenyl-3-hexene 

Relevant articles and documents

Dirhodium(II)-Mediated Alkene Epoxidation with Iodine(III) Oxidants

Dirhodium(II) complexes and iodine(III) oxidants have found useful applications in synthetic nitrene chemistry. In this study, the combination of the dirhodium(II) complex Rh2(tpa)4 (tpa = triphenylacetate) with the iodine(III) oxidant PhI(OPiv)2 is shown to promote the epoxidation of alkenes in the presence of 2 equivalents of water. The reaction can be applied to diversely substituted alkenes and the corresponding epoxides are isolated with yields of up to 90 %. A possible mechanism involves the dirhodium(II) complex as a Lewis acid species that would tune the oxidizing character of the iodine(III) reagent.

Concise synthesis and structure-activity relationship of furospinosulin-1, a hypoxia-selective growth inhibitor from marine sponge

Structure-activity relationship of furospinosulin-1 (1), a hypoxia-selective growth inhibitor isolated from marine sponge, was investigated. Concise synthetic method of 1 was developed, and some structurally modified analogues were prepared. Biological evaluation of them revealed that the whole chemical structure was important for the hypoxia-selective growth inhibitory activity of 1. Among prepared, the desmethyl analogue 30 showed excellent hypoxia-selective inhibitory activity similar to that of 1 and also exhibited in vivo anti-tumor activity with oral administration.

Iridium catalysts with bicyclic pyridine-phosphinite ligands: Asymmetric hydrogenation of olefins and furan derivatives

(Chemical Equation Presented) Superior bicyclics: Iridium catalysts as 1 derived from pyridine-phosphinite ligands considerably extend the scope of asymmetric hydrogenation. In addition to various unfunctionalized and functionalized olefins, furans, and benzofurans, for which no catalysts were known before, are also hydrogenated with high enantioselectivity (see scheme).