748745-97-3Relevant academic research and scientific papers
β-Glucuronyl carbamate based pro-moieties designed for prodrugs in ADEPT
Leenders,Leenders, Ruben G.G.,Gerrits,Gerrits, Kasper A. A.,Ruijtenbeek,Ruijtenbeek, Rob,Scheeren,Scheeren, Hans W.,Haisma,Haisma, Hidde J.,Boven,Boven, Epie
, p. 1701 - 1704 (2007/10/02)
A number of pro-moieties 8a-e designed for prodrug preparation have been synthesized. The pro-moieties, containing a glucuronyl carbamate group linked to a spacer possessing a terminal carboxylic acid group, have been synthesized from isocyanates 6 and an
