74877-07-9

Usage

Uses

Used in Pharmaceutical Industry:
1-(3,4-DICHLORO-PHENYL)-ETHYLAMINE is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, potentially offering novel therapeutic options.
Used in Pesticide Industry:
1-(3,4-DICHLORO-PHENYL)-ETHYLAMINE is used as a precursor in the production of certain pesticides. Its chemical properties may be harnessed to create effective compounds for controlling pests in agriculture, thereby contributing to crop protection and yield enhancement.

InChI:InChI=1/C8H9Cl2N/c1-5(11)6-2-3-7(9)8(10)4-6/h2-5H,11H2,1H3/p+1/t5-/m1/s1

Upstream product

• 139752-39-9 1-(3,4-dichlorophenyl)ethanone oxime 
• 2642-63-9 3',4'-dichloroacetophenone 

Downstream Products

• 132361-84-3 (Z)-3-[1-(3,4-Dichloro-phenyl)-ethylamino]-but-2-enoic acid methylamide 
• 931419-08-8 3'-{[1-(3,4-dichlorophenyl)ethyl]amino}propionitrile 
• 2642-63-9 3',4'-dichloroacetophenone 
• 1624256-29-6 (R,S)-8-(1-(3,4-dichlorophenyl)ethyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrazino[2,1-f]purine-2,4(1H,3H)-dione 
• 1429176-22-6 C₁₈H₂₀Cl₂N₄O₂ 
• 1429176-23-7 (S)-3-(2-((S)-1-(3,4-dichlorophenyl)ethylamino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one 
• 1429176-38-4 C₂₁H₁₈Cl₂N₄O₂ 
• 1429176-39-5 C₂₁H₁₈Cl₂N₄O₂ 
• 1226973-85-8 1-[1-(3,4-dichloro-phenyl)-ethyl]-3-[2-(2,6-dioxo-piperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindol-5-ylmethyl]-urea 
• 1012420-33-5 rac-N-[1-(3,4-dichloro-phenyl)-ethyl]-3-fluoro-benzamide 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS

The present disclosure relates generally to compounds useful in treatment of conditions associated with mutant isocitrate dehydrogenase (mt-IDH), particularly mutant IDH1 enzymes. Specifically, the present invention discloses compound of formula (IA), which exhibits inhibitory activity against mutant IDH1 enzymes. Method of treating conditions associated with excessive activity of mutant IDH1 enzymes with such compound is disclosed. Uses thereof, pharmaceutical composition, and kits are also disclosed.

AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS

The present invention relates to the CCR3 receptor ligands of the general formula (I), within them favourably to antagonists and to the salts, solvates and isomers thereof, to the pharmaceutical compositions containing them, to the use of the compounds of the general formula (I) and their salts, solvates and isomers and to the preparation of the compounds of the general formula (I) and their salts, solvates and isomers and to the new intermediates of the general formula (IIa).

2-Mercaptoimidazoles, a new class of potent CCR2 antagonists

We describe the synthesis and SAR of a new class of CCR2 antagonists based on a 2-mercaptoimidazole scaffold. The initial lead 1a was optimized to the 3,4-disubstituted analogues 1p-(S) and 1q-(S), which have IC50 values in the MCP-1 induced Ca

AMIDE COMPOUND AND METHOD OF CONTROLLING PLANT DISEASE WITH THE SAME

A amid compound of the formula (1): wherein, in the formula, R51 represents a halogen atom, a C1-C6 alkyl group and the like; R52 represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group and the like; R53 represents a halogen atom and the like; R56 represents a halogen atom and the like; R57 represents a hydrogen atom and the like; R58 and R59 independently represent a hydrogen atom, a C1-C3 alkyl group and the like; R60 represents a C1-C4 alkyl group, a C1-C4 haloalkyl group, a C3-C4 alkenyl group, or a C3-C6 alkynyl group; R61 represents a C1-C4 alkyl group, a C1-C4 haloalkyl group, a C3-C4 alkenyl group or a C3-C6 alkynyl group or a C2-C4 cyanoalkyl group; R62, R63 and R64 represent a hydrogen atom, a halogen atom and the like; X represents a oxygen atom or a sulfur atom; has an excellent activity against plant diseases.

N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor

There is disclosed an N-(α-alkylbenzylidene)-α-phenylalkylamine represented by the general formula (1): STR1 wherein R1 represents a lower alkyl group, R2 represents a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group and X represents a halogen atom or a lower alkoxy group, its use and a process for producing the same and processes for producing intermediates therefor.

Triazine derivatives, a process for preparing the derivatives, and herbicides containing the derivatives as the effective component

A triazine derivative represented by the general formula: STR1 wherein R1 and R2 are each an alkyl group having 1 to 4 carbon atoms, and X1 and X2 are each a halogen atom, an alkyl group having 1 to 4 carbon atoms, an alkoxyl group having 1 to 4 carbon atoms, or an alkylthio group having 1 to 4 carbon atoms. This invention also provides a process for efficiently preparing said triazine derivative and a herbicide containing said triazine derivative as effective component.