74878-31-2

Basic information

• Product Name: 3,5-DICHLORO-4-AMINOBENZOIC ACID ETHYL ESTER
• Synonyms: ETHYL 4-AMINO-3,5-DICHLOROBENZOATE;ETHYL 3,5-DICHLORO-4-AMINOBENZOATE;BUTTPARK 41\01-28;3,5-DICHLORO-4-AMINOBENZOIC ACID ETHYL ESTER;4-AMINO-3,5-DICHLOROBENZOIC ACID ETHYL ESTER;Einecs 278-013-8
• CAS NO: 74878-31-2
• Molecular Formula: C₉H₉Cl₂NO₂
• Molecular Weight: 234.08
• EINECS: 278-013-8
• Product Categories: Aromatic Esters
• Mol File: 74878-31-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 353.3°Cat760mmHg
• Flash Point: 167.5°C
• Appearance: /
• Density: 1.376g/cm³
• Vapor Pressure: 3.62E-05mmHg at 25°C
• Refractive Index: 1.581
• CAS DataBase Reference: 3,5-DICHLORO-4-AMINOBENZOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DICHLORO-4-AMINOBENZOIC ACID ETHYL ESTER(74878-31-2)
• EPA Substance Registry System: 3,5-DICHLORO-4-AMINOBENZOIC ACID ETHYL ESTER(74878-31-2)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 74878-31-2(Hazardous Substances Data)

Usage

General Description

3,5-Dichloro-4-aminobenzoic acid ethyl ester, also known as ethyl 3,5-dichloro-4-aminobenzoate, is a chemical compound derived from benzoic acid. It is a derivative of 3,5-dichloro-4-aminobenzoic acid, which is commonly used in the synthesis of pharmaceuticals and agrochemicals. 3,5-DICHLORO-4-AMINOBENZOIC ACID ETHYL ESTER is used as an intermediate in the production of various drugs and pesticides. It is also utilized in the research and development of new pharmaceutical products. The ethyl ester form of 3,5-dichloro-4-aminobenzoic acid allows for easier handling and storage, making it a versatile and important chemical in the pharmaceutical and agricultural industries.

InChI:InChI=1/C9H9Cl2NO2/c1-2-14-9(13)5-3-6(10)8(12)7(11)4-5/h3-4H,2,12H2,1H3

Upstream product

• 7722-84-1 dihydrogen peroxide 
• 94-09-7 p-aminoethylbenzoate 
• 64-17-5 ethanol 
• 56961-25-2 4-amino-3,5-dichlorobenzoic acid 

Downstream Products

• 1621681-27-3 sodium 3,5-dichloro-4-(2-chloro-5-(4-(trifluoromethyl)pyrimidin-2-yl)benzamido)benzoate 
• 1621681-40-0 4-(5-bromo-2-chlorobenzamido)-3,5-dichlorobenzoic acid 
• 1621681-42-2 ethyl 4-(5-bromo-2-methylbenzamido)-3,5-dichlorobenzoate 
• 1621681-28-4 3,5-dichloro-4-(5-(cyclohexylmethyl)-2-methylbenzamido) benzoic acid 

Relevant articles and documents

Substituted benzamides with activity towards EP4 receptors

The present invention belongs to the field of EP4 receptor ligands. More specifically it refers to compounds of general formula (I) having great affinity and selectivity for the EP4 receptor. The invention also refers to the process for their preparation, to their use as medicament for the treatment and/or prophylaxis of diseases or disorders mediated by the EP4 receptor as well as to pharmaceutical compositions comprising them.

Method of lowering intraocular pressure using phenylimino-imidazoles

A method is provided of treating glaucoma in a patient which comprises administering, preferably as eye drops, an effective amount of the compound STR1 which is preferably in the form of its hydrochloride. The compound is administered preferably in the form of a sterile pharmacologically acceptable solution which contains from 0.1 to 5, and more preferably 0.1 to 2.0, percent by weight of said compound. The patient preferably obtains the anti-glaucoma agent in the form of a kit which comprises the sterile pharmacologically acceptable solution and an eyedropper for dispensing said sterile pharmacologically acceptable solution to the affected eyes of a patient suffering from glaucoma.