74878-32-3

Usage

Synonyms

4-amino-3,5-dichlorobenzyl alcohol
N-(3,5-dichloro-4-hydroxyphenyl)-4-aminoaniline

Physical Description

White to off-white crystalline powder

Functional Groups

Phenol group (benzenemethanol)
Aniline group (4-aminoaniline)
Chlorine atoms attached to the benzene ring

Applications

Synthesis of pharmaceuticals
Production of dyes
Organic compound synthesis
Potential applications in antiseptics and disinfectants

Health Hazards

Careful handling required due to potential health hazards

Reactivity

Reactivity should be taken into consideration during handling

Potential Uses

Production of antiseptics
Manufacturing pharmaceutical products

Upstream product

• 41727-48-4 methyl 4-amino-3,5-dichlorobenzoate 
• 7732-18-5 water 
• 56961-25-2 4-amino-3,5-dichlorobenzoic acid 

Downstream Products

• 533914-02-2 2,6-dichloro-4-(1,1,1-triphenylmethoxymethyl)aniline 
• 1213235-02-9 ethyl 1-[1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazol-4-yl]-1H-pyrazole-4-carboxylate 
• 1213234-75-3 (3-{3-[1-(3,4,5-Trichlorobenzyl)-1H-1,2,3-triazol-4-yl]-1,2,4-oxadiazol-5-yl}-1H-pyrazol-1-yl)acetic acid 
• 1213235-12-1 5-(1H-pyrazol-5-yl)-3-[1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazol-4-yl]-1,2,4-oxadiazole 
• 1213235-13-2 ethyl (3-{3-[1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazol-4-yl]-1,2,4-oxadiazol-5-yl}-1H-pyrazol-1-yl)acetate 
• 1213234-76-4 5-{5-[1-(3,4,5-Trichlorobenzyl)-1H-1,2,3-triazol-4-yl]-1,3,4-thiadiazol-2-yl}nicotinic acid 
• 1213235-11-0 N'-hydroxy-1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazole-4-carboximidamide 
• 1213234-97-9 ethyl (5-{2-[1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazol-4-yl]pyrimidin-5-yl}-2H-tetrazol-2-yl)acetate 
• 1213234-71-9 (5-{2-[1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazol-4-yl]-1,3-thiazol-5-yl}-2H-tetrazolyl)acetic acid 
• 1346427-30-2 C₁₀H₈Cl₃N₅O 
• 1213234-93-5 C₁₃H₇Cl₃N₈S 
• 1213235-15-4 methyl 5-[(2-{[1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazol-4-yl]carbonyl}hydrazino)carbonyl]nicotinate 
• 1213235-14-3 1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazole-4-carbohydrazide 
• 1213235-10-9 1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazole-4-carbonitrile 

Relevant academic research and scientific papers

HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE

Heteroaromatic compounds of structural formula I are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and tr

Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitors

It has been demonstrated that once-a-day dosing of systemically-distributed SCD inhibitors leads to adverse events in eye and skin. Herein, we describe our efforts to convert a novel class of systemically-distributed potent triazole-based uHTS hits into liver-targeted SCD inhibitors as a means to circumvent chronic toxicity.

HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE

Heteroaromatic compounds of structural formula (I) are inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD). The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and met

PIPERIDIN-2-ONE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT

A piperidin-2-one derivative compound represented by formula (I): wherein all symbols are described in the specification, or a non-toxic salt thereof. The compound represented by formula (I) inhibits activation of p38MAP kinase, and is useful for preventi

An Efficient Synthesis of Chloroethylclonidine

An efficient pathway for the preparation of chloroethylclonidine dihydrochloride (1) is described.

Pharmacologically active CNS compound

The invention provides a series of compounds of formula (I) and salts thereof, wherein for example,R1 and R2, which may be the same or different each represent -NR13R14 where R13 and R14 may each independently represent hydrogen or alkyl or, taken together with the nitrogen atom to which they are attached form a heterocyclic ring, optionally substituted by one or more alkyl or arylalkyl groups and optionally containing a further heteroatom;, R3 is hydrogen, haloalkyl, alkoxymethyl or alkyl;, R4 is hydrogen, nitro or halo;, R5 is hydrogen or halo;, R6 is hydrogen, halo, nitro, amino, alkylamino or dialkylamino;, R7 is hydrogen or halo;, R8 is hydrogen or halo; The compounds may be used for the treatment or prophylaxis of a neurodegenerative or other neurological disorder of the CNS, the aetiology or which includes excessive release of the neurotransmitter glutamate.

USE OF 2-[(3,5-DIHALO-4-AMINOBENZYL)] IMIDAZOLINES TO STIMULATE ALPHA-1 ADRENERGIC RECEPTORS AND TO TREAT NASAL CONGESTION

Disclosed herein are alpha adrenergic and nasal decongestant compounds of the formula STR1 wherein R 1 and R 2, each being the same or different, are halogens, and the pharmaceutically acceptable salts thereof.