7520-67-4

Usage

Physical properties

Colorless or light yellow liquid with a strong odor

Common uses

Production of pharmaceuticals, pesticides, and other organic compounds

Toxicity

Highly toxic and may cause severe skin and eye irritation, harmful if ingested or inhaled

Classification

Possible carcinogen

Environmental impact

Harmful effects on the environment if released into the air, soil, or water

Safety measures

Important to follow proper safety measures when handling and using Benzenemethanol, 3,4,5-trichloro-

Upstream product

• 51-39-8 3,4,5-trichlorobenzoic acid 
• 21472-86-6 3,4,5-trichloro-toluene 
• 56961-25-2 4-amino-3,5-dichlorobenzoic acid 
• 74878-32-3 4-amino-3,5-dichlorobenzyl alcohol 
• 121-43-7 Trimethyl borate 
• 79185-27-6 3,4,5-trichlorobenzyl chloride 

Downstream Products

• 79185-27-6 3,4,5-trichlorobenzyl chloride 
• 750568-25-3 (1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-(3,4,5-trichloro-benzyloxy)-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid diethyl ester 
• 139256-46-5 (3,4,5-trichloro-phenyl)-acetonitrile 
• 51719-68-7 (3,4,5-trichloro-phenyl)-acetic acid 
• 21472-86-6 3,4,5-trichloro-toluene 
• 1213234-83-3 3,4,5-trichlorobenzyl azide 
• 1213234-84-4 4-(tributylstannyl)-1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazole 
• 1213234-90-2 Methyl 2-[1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazol-4-yl]-1,3-thiazole-5-carboxylate 
• 1213234-91-3 2-[1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazol-4-yl]-1,3-thiazole-5-carboxamide 
• 1213234-92-4 2-[1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazol-4-yl]-1,3-thiazole-5-carbonitrile 
• 1213234-93-5 5-{2-[1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazol-4-yl]-1,3-thiazol-5-yl}-1H-tetrazole 
• 1213234-94-6 ethyl (5-{2-[1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazol-4-yl]-1,3-thiazol-5-yl}-2H-tetrazol-2-yl)acetate 
• 1213234-72-0 (5-{2-[1-(3,4,5-Trichlorobenzyl)-1H-1,2,3-triazol-4-yl]pyrimidin-5-yl}-2H-tetrazol-2-yl)acetic acid 
• 1213234-95-7 2-[1-(3,4,5-trichlorobenzyl)-1H-1,2,3-triazol-4-yl]pyrimidine-5-carbonitrile 

Relevant academic research and scientific papers

HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE

Heteroaromatic compounds of structural formula I are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and tr

Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitors

It has been demonstrated that once-a-day dosing of systemically-distributed SCD inhibitors leads to adverse events in eye and skin. Herein, we describe our efforts to convert a novel class of systemically-distributed potent triazole-based uHTS hits into liver-targeted SCD inhibitors as a means to circumvent chronic toxicity.

HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE

Heteroaromatic compounds of structural formula (I) are inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD). The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and met

Pharmacologically active CNS compound

The invention provides a series of compounds of formula (I) and salts thereof, wherein for example,R1 and R2, which may be the same or different each represent -NR13R14 where R13 and R14 may each independently represent hydrogen or alkyl or, taken together with the nitrogen atom to which they are attached form a heterocyclic ring, optionally substituted by one or more alkyl or arylalkyl groups and optionally containing a further heteroatom;, R3 is hydrogen, haloalkyl, alkoxymethyl or alkyl;, R4 is hydrogen, nitro or halo;, R5 is hydrogen or halo;, R6 is hydrogen, halo, nitro, amino, alkylamino or dialkylamino;, R7 is hydrogen or halo;, R8 is hydrogen or halo; The compounds may be used for the treatment or prophylaxis of a neurodegenerative or other neurological disorder of the CNS, the aetiology or which includes excessive release of the neurotransmitter glutamate.