74897-05-5Relevant academic research and scientific papers
Stereoselective synthesis of disubstituted butadienes via copper-mediated coupling of alkenyl silanes
Blackwell, David T.,Galloway, Warren R. J. D.,Spring, David R.
supporting information; experimental part, p. 2140 - 2144 (2011/11/06)
A strategy is described for the stereoselective synthesis of substituted (E)-, (Z)-, and -disubstituted butadienes from terminal alkynes by the copper-mediated coupling of geometrically-defined alkenyl silanes. Proof-of-concept results that demonstrate the feasibility of this approach are presented. Georg Thieme Verlag Stuttgart · New York.
1H NMR Study of some Substituted Acyclic Silaethanes, 2-Silapropanes and 2-Methyl-2-Silapropanes and their Rotameric Populations around the Si-C Bond
Carleer, Robert,Anteunis, Marc J. O.
, p. 253 - 258 (2007/10/02)
Three series of substituted silaalkanes, (i) SiH3CH2X, (ii) MeSiH2CH2X and (iii) Me2SiHCH2X, have been prepared (X=Cl, Br, I, NMe2, OMe, SMe), and the shifts and coupling constants extracted from their 1H NMR spectra.Coefficients averaged over three rotameric states can be obtained from the first series which are used for the correction of coupling constants resulting from the presence of the electronegative substituents X.With the aid of the Karplus-Conroy angular dependence of the interproton coupling constants in silaethane fragments, corrected for electronegative substitution, approximate rotameric population in series ii and iii were obtained.Except for X=NMe2, there is always a preference for a synclinal X/CH3 relationship, even for sandwiched situation (series iii).
