74900-81-5

Basic information

• Product Name: 3-(ALLYLOXY)ANILINE
• Synonyms: 3-(ALLYLOXY)ANILINE;3-(allyloxy)phenylamine;UKRORGSYN-BB BBV-182193;3-(allyloxy)aniline(SALTDATA: FREE);3-prop-2-enoxyaniline;3-(allyloxy)benzenamine
• CAS NO: 74900-81-5
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.18974
• Mol File: 74900-81-5.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 277°C at 760 mmHg
• Flash Point: 131.2°C
• Appearance: /
• Density: 1.037g/cm³
• Vapor Pressure: 0.00465mmHg at 25°C
• Refractive Index: 1.554
• PKA: 4.35±0.10(Predicted)
• CAS DataBase Reference: 3-(ALLYLOXY)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(ALLYLOXY)ANILINE(74900-81-5)
• EPA Substance Registry System: 3-(ALLYLOXY)ANILINE(74900-81-5)

Safety Data

• Hazardous Substances Data: 74900-81-5(Hazardous Substances Data)

Usage

Uses

3-(Allyloxy)aniline is a reagent in the preparation of Bz-?aminoindoles and Bz-?methoxyindoles.

InChI:InChI=1/C9H11NO/c1-2-6-11-9-5-3-4-8(10)7-9/h2-5,7H,1,6,10H2

Upstream product

• 898161-44-9 tert-butyl (3-(allyloxy)phenyl)carbamate 
• 19962-06-2 tert-butyl 3-hydroxyphenylcarbamate 
• 37439-78-4 N-(3-(allyloxy)phenyl)acetamide 
• 621-42-1 meta-hydroxyacetanilide 
• 554-84-7 meta-nitrophenol 
• 58621-55-9 1-allyloxy-3-nitro-benzene 

Downstream Products

• 892413-66-0 2,4-bis[[3-(2-propenyloxy)phenyl]amino]-5-pyrimidinecarbonitrile 
• 1400812-30-7 4,6-bis{2-[(3-allyloxyphenylimino)methyl]-6-tert-butyl-4-methoxyphenoxy}titanium(IV) dichloride 
• 1400812-02-3 2-{N-[3-(allyloxy)phenyl]iminomethyl}-6-tert-butyl-4-methoxyphenol 

Relevant articles and documents

BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE

Described herein are bifunctional degrader compounds, their various targets, their preparation, pharmaceutical compositions comprising them, and their use in the treatment of conditions, diseases, and disorders mediated by various target proteins.

Silver-Mediated Trifluoromethoxylation of (Hetero)aryldiazonium Tetrafluoroborates

Here we report a silver-mediated trifluoromethoxylation of (hetero)aryldiazonium tetrafluoroborates by converting an aromatic amino group into an OCF3 group. This method, which can be considered to be a trifluoromethoxylation variation of the classic Sandmeyer-type reaction, uses readily available aryl and heteroaromatic amines as starting materials and AgOCF3 as trifluoromethoxylating reagents. The broad substrate scope and simple, mild reaction condition made this transformation a valuable method in constructing aryl-OCF3 bonds.

MACROCYCLIC KINASE INHIBITORS AND USES THEREOF

The present disclosure provides macrocyclic compounds of Formula (I). The provided compounds are able to bind protein kinases and may be useful in modulating (e.g., inhibiting) the activity of a protein kinase in a subject or cell and/or in treating or pr