749187-35-7

Basic information

• Product Name: (1R,2S) ethyl 2-amino-1-cyclohex-4-enecarboxylate
• CAS NO: 749187-35-7
• Molecular Weight: 169.224
• Mol File: 749187-35-7.mol

Chemical Properties

• CAS DataBase Reference: (1R,2S) ethyl 2-amino-1-cyclohex-4-enecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S) ethyl 2-amino-1-cyclohex-4-enecarboxylate(749187-35-7)
• EPA Substance Registry System: (1R,2S) ethyl 2-amino-1-cyclohex-4-enecarboxylate(749187-35-7)

Safety Data

• Hazardous Substances Data: 749187-35-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(1R,2S) ethyl 2-amino-1-cyclohex-4-enecarboxylate is used as an intermediate in the synthesis of pharmaceuticals for its potential applications in the development of new drugs. Its unique structure allows it to be a versatile building block in various chemical reactions and processes for the production of complex molecules.
Used in Organic Compounds Synthesis:
(1R,2S) ethyl 2-amino-1-cyclohex-4-enecarboxylate is used as an intermediate in the synthesis of other organic compounds, taking advantage of its cyclohexene ring and functional groups to create a wide range of molecules with different properties and applications.

Upstream product

• 859176-88-8 cis-6-amino-cyclohex-3-enecarboxylic acid ethyl ester hydrochloride 
• 57266-62-3 ethyl cis-(2-aminocyclohex-4-ene)-1-carboxylate 

Relevant articles and documents

Efficient synthesis of 3,4- and 4,5-dihydroxy-2-amino-cyclohexanecarboxylic acid enantiomers

An efficient method for the synthesis of (1S,2R,4R,5S)- and (1R,2R,4R,5S)-2-amino-4,5-dihydroxycyclohexanecarboxylic acids (-)-6 and (-)-9 and (1R,2R,3S,4R)- and (1S,2R,3S,4R)-2-amino-3,4-dihydroxycyclohexanecarboxylic acids (-)-15 and (-)-18 was develope

Approach to highly enantiopure β-amino acid esters by using lipase catalysis in organic media

Ethyl esters of ten alicyclic β-aminocarboxylic acids were resolved by lipase catalysis in organic solvents. The resolution was based on acylation of the amino group at the R-stereogenic centre with various 2,2,2- trifluoroethyl esters. An increase in the hydrophobic nature of the acyl donor enhanced the enantioselectivity and reactivity in the case of lipase SP 526 from Candida antarctica, while the opposite effect was observed with lipase PS from Pseudomonas cepacia. An unexceptional enantioselectivity enhancement was observed when 2,2,2-trifluoroethyl chloroacetate was used in the case of lipase PS catalysis.