7492-88-8

Usage

Uses

Used in Pharmaceutical Industry:
3-Piperidinecarbonitrile is used as an intermediate in the synthesis of pyrazolopyrimidine Janus kinase (JAK) inhibitors. These inhibitors are crucial for the treatment of JAK-associated diseases, as they help modulate the JAK/STAT signaling pathway, which plays a significant role in immune response and cell growth regulation.
Used in Antiviral Applications:
In the field of antiviral drug development, 3-Piperidinecarbonitrile is utilized in the synthesis of triazines and related compounds. These compounds exhibit antiviral properties, particularly against Hepatitis C virus (HCV) infection and its associated disorders. By targeting the viral replication process or interfering with essential host factors, these antiviral agents can help manage and treat HCV infections more effectively.

InChI:InChI=1/C6H10N2/c7-4-6-2-1-3-8-5-6/h6,8H,1-3,5H2

Upstream product

• 91419-53-3 (+/-)-2-N-tert-butoxycabonylpiperidine-3-carbonitrile 

Downstream Products

• 724471-23-2 1-[7-(2-bromo-4-trifluoromethylphenyl)-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl]piperidine-3-carbonitrile 
• 724471-24-3 1-[7-(2-bromo-4-trifluoromethylphenyl)-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl]piperidine-3-carbonitrile 
• 1185189-58-5 5-(3-cyanopiperidin-1-ylmethyl)-4-(3,5-dimethylphenoxy)-3-iodo-6-methylpyridin-2(1H)-one 
• 1602922-69-9 (4-chlorophenyl)-carbamic acid 1-(3-cyanopiperidin-1-ylmethyl)-2,2,2-trifluoroethyl ester 

Relevant academic research and scientific papers

COSMETIC COMPOSITIONS WITH TRICYCLODECANE AMIDES

The invention is directed to a cosmetic composition and the precursor thereof. The composition has solid agent and liquid agent, both of which are cosmetic benefit ingredients. The solubility of solid agents in liquid agents in the inventive compositions is enhanced in the presence of a tricyclodecane amide.

PHOTOPROTECTIVE COMPOSITIONS WITH TRICYCLODECANE AMIDES

A personal care photoprotective composition is provided having a UV-A and UV-B sunscreen in conjunction with a tricyclodecane amide. The tricyclodecane amide functions to boost UV-A, UV-B and SPF performance when the personal care composition is applied to skin or hair of the human body.

PROLONGED DELIVERY OF CERTAIN FRAGRANCE COMPONENTS FROM PERSONAL CARE COMPOSITIONS

A personal care composition is provided having a highly volatile fragrance which incorporates alpha pinene, beta pinene, hexyl acetate, limonene, (+) –citronellal, dihydromyrcenol, alpha citronellol, beta citronellol, genaniol, lilial or combinations thereof in conjunction with tricyclodecane amide. The tricyclodecane amide functions to prevent fast volatilization of the highly volatile fragrance components when the personal care composition is applied to skin or hair of the human body.