74925-37-4Relevant academic research and scientific papers
SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF
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, (2018/04/27)
The present invention covers substituted 6-(1H-pyrazol-1-yl)pyrimidin-4-amine compounds of general formula (I) as described and defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular and renal diseases, as a sole agent or in combination with other active ingredients.
On the Reaction of Some 2H-Pyran-2-one Derivatives with Primary Amines
Kvita, Vratislav,Sauter, Hanspeter,Rihs, Grety
, p. 407 - 416 (2007/10/02)
The versatile reactivity of 6-unsubstituted 2H-pyran-2-ones towards aliphatic and aromatic amines has been studied.It was found that the result of the reaction depends not only on the substitution of 2H-pyran-2-ones and on the structure of amines, but also on the stoichiometric ratio of reacting compounds.
