749269-83-8 Usage
General Description
"CHF 5074" is a chemical compound that belongs to the class of phosphodiesterase-4 (PDE4) inhibitors. It has shown anti-inflammatory and bronchodilatory effects in preclinical studies, suggesting potential as a treatment for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma. CHF 5074 has been found to inhibit the production of inflammatory mediators and reduce airway inflammation in animal models, making it a promising candidate for the development of new therapies for these conditions. Additionally, it has shown potential for improving lung function and reducing airway hyperresponsiveness, further supporting its potential as a therapeutic agent for respiratory diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 749269-83-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,9,2,6 and 9 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 749269-83:
(8*7)+(7*4)+(6*9)+(5*2)+(4*6)+(3*9)+(2*8)+(1*3)=218
218 % 10 = 8
So 749269-83-8 is a valid CAS Registry Number.
749269-83-8Relevant articles and documents
1-(2-FLUOROBIPHENYL-4-YL)-ALKYL CARBOXYLIC ACID DERIVATIVES FOR THE THERAPY OF TRANSTHYRETIN AMYLOIDOSIS
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, (2011/11/06)
Derivatives of 1-(2-fluorobiphenyl-4-yl)-alkyl carboxylic acid are capable of stabilizing the tetrameric native state of transthyretin for the prophylaxis and treatment of amyloidosis.
