74927-02-9

Basic information

• Product Name: 2,6-bis(1-methylbutyl)phenol
• Synonyms: 2,6-di(pentan-2-yl)phenol; phenol, 2,6-bis(1-methylbutyl)-
• CAS NO: 74927-02-9
• Molecular Formula: C₁₆H₂₆O
• Molecular Weight: 234.377
• Mol File: 74927-02-9.mol

Chemical Properties

• Boiling Point: 312.1°C at 760 mmHg
• Flash Point: 145.5°C
• Density: 0.922g/cm³
• Vapor Pressure: 0.000295mmHg at 25°C
• Refractive Index: 1.502
• CAS DataBase Reference: 2,6-bis(1-methylbutyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-bis(1-methylbutyl)phenol(74927-02-9)
• EPA Substance Registry System: 2,6-bis(1-methylbutyl)phenol(74927-02-9)

Safety Data

• Hazardous Substances Data: 74927-02-9(Hazardous Substances Data)

Usage

Uses

Used in Lubricant Industry:
2,6-bis(1-methylbutyl)phenol is used as an additive in lubricants for its ability to improve the performance and longevity of the lubricant. It is particularly favored in industrial and automotive applications where enhanced lubrication is crucial for machinery operation and maintenance.
Used in Polymer and Plastic Industry:
2,6-bis(1-methylbutyl)phenol is used as an antioxidant and UV stabilizer in various polymer and plastic products. Its inclusion helps to prevent degradation caused by exposure to oxygen and ultraviolet light, thereby extending the lifespan and maintaining the integrity of these materials.

Upstream product

• 109-67-1 1-penten 
• 87-26-3 methylbutylphenol 
• 96-17-3 2-Methylbutyraldehyde 
• 108-94-1 cyclohexanone 

Relevant articles and documents

Facile Synthesis of 2,6-Dialkylphenols by Cross-Aromatization of Cyclohexanones with Aldehydes Catalyzed by Zirconocene Complexes

2,6-Dialkylphenols, which are difficult to prepare by conventional methods, have been conveniently synthesized in one step via zirconocene-catalyzed cross-aromatization of cyclohexanones with aldehydes.

Synthesis, Biological Evaluation, and Preliminary Structure-Activity Considerations of a Series of Alkylphenols as Intravenous Anesthetic Agents

Following our discovery of the intravenous (iv) anesthetic activity of 2,6-diethylphenol in mice, a series of alkylphenols was examined in this species and the most active analogues were further evaluated in rabbits.The synthesis of compounds which were not commercially available was accomplished by adaptations of standard ortho-alkylation procedures for phenols.Structure-activity relationships were found to be complex, but, in general, potency and kinetics appeared to be a function of both the lipophilic character and the degree of steric hindrance exerted by ortho substituents.The most interesting compounds were found in the 2,6-dialkyl series, and the greatest potency was associated with 2,6-di-sec-alkyl substitution.In particular, 2,6-diisopropylphenol (ICI 35868) emerged as a candidate for further development and has subsequently been shown to be an effective iv anesthetic agent in man.