87-26-3

Usage

Uses

Used in Pharmaceutical Industry:
2-(1-METHYLBUTYL)PHENOL is used as an intermediate in the synthesis of Dinosam (D409730), which is utilized in the preparation of Chitosan gel. This gel is applied in shampoos for preventing alopecia, making it a valuable component in hair care products.
Used in Agricultural Industry:
2-(1-METHYLBUTYL)PHENOL is used in methods and formulations for preventing the downward migration of agricultural materials. This application helps in maintaining the effectiveness and longevity of agricultural products.
Used in Paint and Coating Industry:
2-(1-METHYLBUTYL)PHENOL is used as a dispersing and mixing agent for paint pastes, ensuring a uniform distribution of pigments and other components. It also serves as an antiskinning agent for paint, varnish, and oleoresinous enamels, preventing the formation of a skin on the surface of these materials during their application.
Used in Organic Synthesis:
2-(1-METHYLBUTYL)PHENOL is employed as a key component in various organic synthesis processes, contributing to the development of new compounds and materials with diverse applications across different industries.

InChI:InChI=1/C11H16O/c1-3-6-9(2)10-7-4-5-8-11(10)12/h4-5,7-9,12H,3,6H2,1-2H3/t9-/m0/s1

Upstream product

• 6032-29-7 (+/-)-2-pentanol 
• 108-95-2 phenol 
• 94-06-4 2-(4-Hydroxyphenyl)pentane 
• 73377-38-5 5,6,8,9-tetrahydro-7-phenyldibenzoxanthyilium triflouromethanesulphonate 
• 625-30-9 2-pentylamine 
• 4125-49-9 2-<2-Methoxyphenyl>-pentan 
• 107-87-9 2-Pentanone 
• 91763-96-1 2-(2-Methoxy-phenyl)-pentanol-⁽²⁾ 
• 118452-82-7 2-(2-Methoxyphenyl)-penten-⁽²⁾ 
• 109-67-1 1-penten 

Downstream Products

• 74927-02-9 2,6-di-sec-pentylphenol 
• 94-06-4 2-(4-Hydroxyphenyl)pentane 
• 74926-92-4 2-ethyl-6-(1-methylbutyl)phenol 
• 4097-36-3 2-sec-amyl-4,6-dinitrophenol 

Relevant academic research and scientific papers

Preparation method of dinosam compound

The invention discloses a preparation method of a dinosam compound, which comprises the following steps: S1) adding phenol, 1-pentene and a rhenium catalyst into a reaction container, and conducting reacting at the temperature of 130-150 DEG C under protective gas; S2) diluting the obtained material with ethyl acetate, conducting washing with water, conducting separating to obtain an organic phase, and conducting drying, filtering and concentrating to obtain a 2-(pent-2-yl)phenol compound; S3) adding a mixed solution of nitric acid and methanesulfonic acid into the reactor, conducting heating to 40-50 DEG C, and dropwise adding the 2-(pent-2-yl)phenol compound into the reactor; and S4) diluting the material obtained in the step S3) with ethyl acetate, conducting washing with water, conducting separating to obtain an organic phase, and conducting drying, filtering and concentrating to obtain the 2,4-dinitro-6-(pent-2-yl)phenol. The method has the advantages of easily available raw materials, high yield, mild reaction conditions and strong specificity; and the method has good regioselectivity, is simple and convenient in post-treatment, and is green and environment-friendly.

Metal cation-exchanged montmorillonite (Mn+-mont)-catalysed aromatic alkylation with aldehydes and ketones

The alkylation of aromatic compounds with aldehydes and ketones in the presence of a variety of metal cation-exchanged montmorillonites (Mn+-mont; Mn+ = Zr4+, Al3+, Fe3+, Zn2+, H+, Na+) has been investigated. Al3+- and Zr4+-Monts are revealed to be effective as catalysts, while no reaction takes place with Na+-mont. Al3+-Mont-catalysed alkylation of phenol with several aldehydes produces mainly or almost solely the corresponding gem-bis(hydroxyphenyl)alkanes (bisphenols) in good yields, while that with several ketones affords selectively the corresponding alkylphenols in moderate to good yields. The alkylation always occurs at the carbonyl carbon without any skeletal rearrangement and the kind of products depends much on the steric hindrance of an electrophilic intermediary carbocation. The alkylation of anisole, veratrole and p-cresol proceeds well, while that of toluene, benzene, chlorobenzene and nitrobenzene scarcely occurs.

Equilibria for the isomerization of (secondary-alkyl)phenols and cyclohexylphenols

Equilibria of a series of isomerizations and trans-alkylations of alkylphenols have been investigated in the liquid phase over a wide range of temperatures.Equilibria of isomerizations connected with the displacement of a substituent on a benzene nucleus were studied for secondary-butyl, -amyl, -hexyl, and cyclohexyl-phenols, and di-(secondary-butyl)phenols.Equilibria of positional isomerization connected with the displacement of an oxyphenyl radical in an alkyl chain were investigated for oxyphenyl-pentanes, -hexanes, -octanes, and -decanes.Trans-alkylation was investigated for di- and tri-(secondary-butyl)phenols.Values of ΔrH0m and ΔrS0m were found for all investigated reactions.An analysis was made of the thermodynamic quantities for the reactions.Enthalpies of formation of isopropylphenols (IPP) in the gaseous state were calculated.The values of ΔfH0m/(kJ * mol-1) were found at 298.15 K: o-IPP, -(175.3 +/- 2.4); p-IPP, -(175.3 +/- 2.4); m-IPP, -(175.3 +/-2.4); 2,4-di-IPP, -(254.1 +/- 2.8); 2,5-di-IPP, -(254.1 +/- 2.8); 2,6-di-IPP, -(254.1 +/- 2.8); 3,5-di-IPP, -(254.1 +/- 2.8); 2,4,6-tri-IPP, -(333.0 +/- 3.1).

Nucleophilic Displacement with Heterocycles as Leaving Groups. Part 16. Reactions of Secondary Alkyl Primary Amines with 5,6,8,9-Tetrahydro-7-phenyldibenzoxanthylium Trifluoromethanesulphonate to give Intermediates Solvolysing without Rearrangement

Representative secondary alkyl primary amines R1R2CHNH2 react with the title pyrylium cation in acetic acid, alcohols, phenols, and NN-dimethylaniline acting as nucleophilic solvents to give O- and C-(secondary alkyl) products.Absence of carbenium ion rearrangements is consistent with reaction via intimate ion-molecule pairs formed rapidly from the corresponding pyridinium cations.