74938-33-3

Basic information

• Product Name: 1,2,4,5-tetrahydro-1,3-dimethyl-3H-3-benzazepin-2-one
• CAS NO: 74938-33-3
• Molecular Weight: 189.257
• Mol File: 74938-33-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2,4,5-tetrahydro-1,3-dimethyl-3H-3-benzazepin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4,5-tetrahydro-1,3-dimethyl-3H-3-benzazepin-2-one(74938-33-3)
• EPA Substance Registry System: 1,2,4,5-tetrahydro-1,3-dimethyl-3H-3-benzazepin-2-one(74938-33-3)

Safety Data

• Hazardous Substances Data: 74938-33-3(Hazardous Substances Data)

Upstream product

• 15987-50-5 1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one 
• 74-88-4 methyl iodide 

Relevant articles and documents

BENZOLACTAMS-1. ALKYLATION OF 1,2,4,5-TETRAHYDRO-3-METHYL-3H-3-BENZAZEPIN-2-ONE WITH SODIUM HYDRIDE AND ALKYL HALIDE

Alkylation of 1,2,4,5-tetrahydro-3-methyl-3H-3-benzazepin-2-one 1a with various halides and sodium hydride in tetrahydrofuran-dimethylformamide solvent system was studied.Primary halides predominantly provided the 1-mono-substituted products, such as alkyl (2a-g,p,q), allyl (2j,k), propargyl (2l) and benzyl (2m-o) derivatives, in satisfactory yields, and secondary halides resulted in lower yields (2h,i) than primary halides.In attempted dialkylations with ω,ω'-dibromoalkanes, 5- and 6-membered spiro products (4c,d) were obtained by this method.The Michael type addition reaction was also studied and it was found that acrylic acid esters gave the corresponding adducts (2p,q).