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2-bromo-1-(3,4-dichlorophenyl)ethanol is an organic compound with the molecular formula C8H7BrCl2O. It is a colorless to pale yellow liquid with a molecular weight of 260.45 g/mol. This chemical features a 2-bromoethyl group attached to a 3,4-dichlorophenyl ring, which gives it unique properties and potential applications in various fields. It is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactive bromine and chlorine atoms, it can undergo various chemical reactions, such as nucleophilic substitution, addition, and elimination reactions. The compound is sensitive to light and heat, and it is recommended to store it in a cool, dry place, away from direct sunlight.

7495-24-1

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7495-24-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7495-24-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,9 and 5 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7495-24:
(6*7)+(5*4)+(4*9)+(3*5)+(2*2)+(1*4)=121
121 % 10 = 1
So 7495-24-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H7BrCl2O/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,12H,4H2

7495-24-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-bromo-1-(3,4-dichlorophenyl)ethanol

1.2 Other means of identification

Product number -
Other names (+-)-2-Brom-1-hydroxy-1-(3.4-dichlor-phenyl)-aethan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7495-24-1 SDS

7495-24-1Relevant academic research and scientific papers

Synthesis of Substituted 1,4-Dioxenes through O-H Insertion and Cyclization Using Keto-Diazo Compounds

Davis, Owen A.,Croft, Rosemary A.,Bull, James A.

, p. 11477 - 11488 (2016/11/28)

1,4-Dioxenes present interesting potential as synthetic intermediates and as unusual motifs for incorporation into biologically active compounds. Here, an efficient synthesis of functionalized 1,4-dioxenes is achieved in two steps. Using keto-diazo compounds, a ruthenium catalyzed O-H insertion with β-halohydrins followed by treatment with base results in cyclization with excellent selectivity, through O-alkylation of the keto-enolate. A variety of halohydrins and anion-stabilizing groups in the diazo-component are tolerated, affording novel functionalized dioxenes. Enantioenriched β-bromohydrins provide enantioenriched 1,4-dioxenes.

Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7

Ren, Chunyan,Smith, Steven G.,Yap, Kyoko,Li, Side,Li, Jiaojie,Mezei, Mihaly,Rodriguez, Yoel,Vincek, Adam,Aguilo, Francesca,Walsh, Martin J.,Zhou, Ming-Ming

supporting information, p. 601 - 605 (2016/07/06)

The chromobox 7 (CBX7) protein of the polycomb repressive complex 1 (PRC1) functions to repress transcription of tumor suppressor p16INK4a through long noncoding RNA, ANRIL (antisense noncoding RNA in the INK4 locus) directed chromodomain (ChD)

Synthesis of optically active α-bromohydrins via reduction of α-bromoacetophenone analogues catalyzed by an isolated carbonyl reductase

Ren, Jie,Dong, Wenyue,Yu, Benqing,Wu, Qiaqing,Zhu, Dunming

body text, p. 497 - 500 (2012/07/28)

Enantiomerically pure (S)-α-bromohydrins were prepared by the reduction of α-bromoacetophenone analogues catalyzed by an isolated carbonyl reductase from Candida magnolia with high yield and excellent enantiomeric excess when methyl tert-butyl ether was employed as the co-solvent, while avoiding the formation of by-products. This provides a new approach to access these chiral α-bromohydrins which are of pharmaceutical importance.

Thrombin receptor antagonists

-

, (2008/06/13)

A thrombin receptor antagonist having the formula useful for inhibiting the aggregation of blood platelets. The compounds can be used in a method of acting upon a thrombin receptor which comprises administering a therapeutically effective but non-toxic am

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