74959-65-2

Usage

Uses

Used in Pharmaceutical and Chemical Research:
2-(4-chlorobenzylidene)-N-phenylhydrazinecarbothioamide is used as a starting material for the synthesis of various compounds, playing a crucial role in the development of new pharmaceuticals and chemical products.
Used in Synthesis of Sulfonamide and Thiazole Derivatives:
In the field of organic chemistry, 2-(4-chlorobenzylidene)-N-phenylhydrazinecarbothioamide is employed as a reagent for the synthesis of sulfonamide and thiazole derivatives, which are important classes of compounds with diverse applications in medicine and industry.
Used as a Potential Anti-tumor and Anti-inflammatory Agent:
2-(4-chlorobenzylidene)-N-phenylhydrazinecarbothioamide has demonstrated potential as an anti-tumor and anti-inflammatory agent, making it a valuable compound in the search for new treatments for cancer and inflammatory diseases.
Used in Antifungal and Antimicrobial Applications:
Studies have shown that 2-(4-chlorobenzylidene)-N-phenylhydrazinecarbothioamide possesses antifungal and antimicrobial activities, indicating its potential use in the development of new anti-infective agents to combat resistant strains of fungi and bacteria.

Upstream product

• 108-94-1 cyclohexanone 
• 104-88-1 4-chlorobenzaldehyde 
• 83639-14-9 2,4-bis(4-chlorophenyl)-3-azabicyclo[3.3.1]nonan-9-one 
• 5351-69-9 4-Phenyl-3-thiosemicarbazide 

Downstream Products

• 74970-91-5 5-(4-chlorophenyl)-N-phenyl-1,3,4-thiadiazol-2-amine 
• 1174624-71-5 ethyl 3-amino-6-(4-chlorophenyl)-5-cyanopyridazine-4-carboxylate 
• 1174624-65-7 ethyl [3-(4-chlorophenyl)-4-oxo-1-(phenylthiocarbamoyl)-4,5-dihydro-1H-pyrazol-5-ylidene]cyanoacetate 
• 1174624-59-9 methyl [3-(4-chlorophenyl)-4-oxo-1-(phenylthiocarbamoyl)-4,5-dihydro-1H-pyrazol-5-ylidene]ethanoate 
• 1093399-42-8 3-(4-chlorophenyl)-4a-hydroxyindeno[2,1-e][1,3,4]oxadiazin-9(4aH)-one 
• 1093399-45-1 3-cyano-4-oxo-N-phenylideno[1,2-c]pyrazole-1(4H)-carbothioamide 
• 1093399-54-2 4-amino-1-(4-chlorobenzoyl)-2,7-dinitro-4'-phenylspiro(fluoren-9,3'-[1,2,4]triazolidine)-5'-thione 
• 84409-01-8 4-amino-2,7-dinitro-9-fluorenone 
• 74970-91-5 phenyl-(5-(4-chlorophenyl)-3H-[1,3,4]thiadiazol-2-ylidene)amine 
• 113432-15-8 {Zn(ClC₆H₄CHNNC(S)NHC₆H₅)2} 
• 113476-54-3 {Ni(ClC₆H₄CHNNC(S)NHC₆H₅)2} 
• 113476-52-1 {Co(ClC₆H₄CHNNC(S)NHC₆H₅)2(H₂O)2} 
• 113407-14-0 Cu(ClC₆H₄CHNNHC(S)NHC₆H₅)2(CH₃COO)2 

Relevant academic research and scientific papers

Synthesis and biological evaluation of novel tetranuclear cyclopalladated complex bearing thiosemicarbazone scaffold ligand: Interactions with double-strand DNA, coronavirus, and molecular modeling studies

Threading intercalators are a novel class of materials that carry two substituents along the diagonal positions of an aromatic ring. When bound to DNA, these substituents project out in DNA grooves. Tetranuclear complexes appear to be promising threading

Synthesis and antimicrobial studies of novel 2,4-diaryl-3-azabicyclo[3.3.1] nonan-9-one 4′-phenylthiosemicarbazones

New series of 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-one 4′-phenylthiosemicarbazones (compounds 9-16) was obtained from the corresponding 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ones. The synthesized compounds have been characterized by their elemental, anal

On the Reaction of Derivatives of Thiosemicarbazide with Bis-Imidochlorides of Oxalic Acid

Arylsubstituted oxalic bis-imidochlorides 1 react with thiosemicarbazones of type 5 as well as 13 to give five-membered-ring heterocycles 8, 11, and 16. 13C-NMR spectroscopy, chemical methods and X-ray crystallography have been used to investigate the nature of the structures obtained.The 13C-chemical shifts of 13 and imidazolidines 16 are correlated with Hammett ?p constants and dual substituent parameters to evaluate the transmission of the X substituent electronic effects via the side-chain iminyl carbon atom into the heterocyclic ring and its neighbouring phenyl groups. - Keywords. 13C-NMR, Derivatives of oxalic acid; DSP-Analysis; NS-Heterocycles; Thiosemicarbazones; X-Ray crystallography.

Studies of Bivalent Metal Complexes of p-Chloro- and p-Methoxy-benzylidene-4-phenylthiosemicarbazone

Bivalent metal complexes of p-chloro- and p-methoxy-benzylidene-4-phenylthiosemicarbazones (H2CBPT and H2MBPT = H2L) have been prepared.The complexes prepared are of the types M(HL)2*nH2O (M = Co, Ni or Zn, n = 0-2), M(HL)X*nH2O (M = Cu or Hg; X = Cl or A