74960-46-6

Usage

Uses

Used in Pharmaceutical Industry:
3-Chloro-1H-indole-2-carbonitrile is used as an intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into various drug molecules, contributing to the development of new medications.
Used in Agrochemical Industry:
3-Chloro-1H-indole-2-carbonitrile is used as an intermediate in the synthesis of agrochemicals for its potential to be part of compounds that can be utilized in agricultural applications, such as pesticides or herbicides.
Used in Organic Synthesis:
3-Chloro-1H-indole-2-carbonitrile is used as a building block in organic synthesis for its structural properties that allow for the production of a wide range of compounds, expanding the scope of chemical research and development.
Used in Drug Development:
3-Chloro-1H-indole-2-carbonitrile is used as a potential candidate for drug development due to its reported biological activities, such as cytotoxic and antitumor effects, which can be harnessed for the creation of new therapeutic agents.

Upstream product

• 74960-45-5 5-chloro-2-cyano-3,1-benzoxazepine 
• 942433-61-6 3-chloro-1H-indole-2-carboxylic acid amide 
• 1477-50-5 Indole-2-carboxylic acid 
• 28737-32-8 3-chloro-1H-indole-2-carboxylic acid 

Downstream Products

• 1374452-11-5 [4-(3-chloro-2-cyano-indol-1-yl)-benzyl]-carbamic acid tert-butyl ester 
• 1374453-31-2 1-(2,2,2-trifluoro-acetylamino)-cyclopropanecarboxylic acid 4-[3-chloro-2-(2-methyl-2H-tetrazol-5-yl)-indol-1-yl]-benzylamide 
• 1374453-33-4 3-methoxy-isoxazole-5-carboxylic acid (1-{4-[3-chloro-2-(2-methyl-2H-tetrazol-5-yl)-indol-1-yl]-benzylcarbamoyl}-cyclopropyl)-amide 
• 1374453-51-6 3-methoxy-isoxazole-5-carboxylic acid (1-{4-[3-chloro-2-(5-methyl-[1,2,4]oxadiazol-3-yl)-indol-1-yl]-benzylcarbamoyl}-cyclopropyl)-amide 
• 1374454-22-4 3-propyl-isoxazole-5-carboxylic acid (1-{4-[3-chloro-2-(5-methyl-[1,2,4]oxadiazol-3-yl)-indol-1-yl]-benzylcarbamoyl}-cyclopropyl)-amide 
• 1374455-32-9 isoxazole-5-carboxylic acid (1-{4-[3-chloro-2-(5-methyl-[1,2,4]oxadiazol-3-yl)-indol-1-yl]-benzylcarbamoyl}-cyclopropyl)-amide 
• 1374451-87-2 {4-[3-chloro-2-(2-methyl-2H-tetrazol-5-yl)-indol-1-yl]-benzyl}-carbamic acid tert-butyl ester 
• 1374451-90-7 1-{4-[3-chloro-2-(2-methyl-2H-tetrazol-5-yl)-indol-1-yl]-benzylcarbamoyl}-cyclopropyl-carbamic acid tert-butyl ester 
• 1374452-04-6 4-[3-chloro-2-(5-methyl-[1,2,4]oxadiazol-3-yl)-indol-1-yl]-benzylamine hydrochloride 
• 1374452-05-7 (1-{4-[3-chloro-2-(5-methyl-[1,2,4]oxadiazol-3-yl)-indol-1-yl]-benzylcarbamoyl}-cyclopropyl)-carbamic acid tert-butyl ester 
• 1374452-01-3 1-amino-cyclopropanecarboxylic acid 4-[3-chloro-2-(5-methyl-[1,2,4]oxadiazol-3-yl)-indol-1-yl]-benzylamide 
• 1374452-02-4 3-chloro-N-hydroxy-1H-indole-2-carboxamidine 

Relevant academic research and scientific papers

INDOLE DERIVATIVES

The present invention relates to the indole derivatives of formula (I), wherein R1-R6 and X are defined in the claims and optical antipodes or racemates and/or salts thereof which are selective antagonists of bradykinin B1 to process for producing these compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.

INDOLE DERIVATIVES

The present invention relates to the indole derivatives of formula (I), wherein R1- R6 and X are defined in the claims and optical antipodes or racemates and/or salts thereof which are selective antagonists of bradykinin B1 to process for producing these compounds, pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.