74963-05-6Relevant academic research and scientific papers
Metal-free arylation of pyrimidines through a photochemical process
Ruch, Jonas,Aubin, Ariane,Erbland, Guillaume,Fortunato, Audrey,Goddard, Jean-Philippe
supporting information, p. 2326 - 2329 (2016/02/18)
Pyrimidinyl and pyrazinyl radicals were generated under moderate energetic irradiation conditions (UVA), and proved to be prompt to undergo C-C bond formation processes. Hetero-biaryl derivatives were obtained in good to high yields with highly interesting functional group selectivities. Bis hetero-biaryls were also easily accessible leading to original compounds, ready for further transformations. Experiments supporting radical processes have been reported.
Electronic Effects of Aryl and Heteroaryl Groups on the Rate of Quaternization of 5-Aryl(or Heteroaryl)pyrimidines
Allen, David W.,Buckland, David J.,Hutley, Barrie G.
, p. 468 - 470 (2007/10/02)
The kinetics of quaternization of a series of 5-aryl- and 5-heteroarylpyrimidines with phenacyl bromide in acetonitrile have been studied in order to assess the electronic effects of the 5-substituent.The observed order of reactivity is 5-(1-methylpyrrol-
