74963-19-2Relevant articles and documents
Electronic Effects of Aryl and Heteroaryl Groups on the Rate of Nucleophilic Displacement of Chlorine from 5-Heteroaryl(or Aryl)-2-chloropyrimidines by Piperidine
Allen, David W.,Buckland, David J.,Hutley, Barrie G.
, p. 463 - 467 (2007/10/02)
The kinetics of nucleophilic displacement of chlorine from a series of 2-chloro-5-heteroaryl(or aryl)pyrimidines by piperidine have been studied in order to assess the electronic effects of the 5-substituent.The observed order of reactivity is 5-(1-methyl