74966-71-5Relevant academic research and scientific papers
Iron(III) catalyzed halo-functionalization of alkynes
Catano, Bryant,Lee, John,Kim, Claudia,Farrell, David,Petersen, Jeffrey L.,Xing, Yalan
supporting information, p. 4124 - 4127 (2015/08/03)
Abstract Aromatic and aliphatic alkynes can be halo-functionalized to α,α-dihalodimethyl ketals catalyzed by FeCl3 in excellent yields. MeOH is used as a nucleophilic solvent and N-halosuccinimide as the halogen source for this efficient transformation. The resulting α,α-dibromodimethyl ketals can be converted to the corresponding α,α-dibromoketones by treatment with 8% FeCl3 in silica gel.
m-Iodosylbenzoic acid, a tagged hypervalent iodine reagent for the iodo-functionalization of alkenes and alkynes
Yusubov, Mekhman S.,Yusubova, Roza Ya.,Kirschning, Andreas,Park, Joo Yeon,Chi, Ki-Whan
, p. 1506 - 1509 (2008/09/19)
An efficient and facile method for the iodo-functionalization of alkenes 5 and alkynes 6 by using recyclable m-iodosylbenzoic acid (2) was developed. The final products can be easily isolated without any chromatographic purification by simple treatment of the crude mixture with an anionic exchange resin. Unreacted m-iodosylbenzoic acid and reduced m-iodobenzoic acid are effectively recovered from the resin by acidification with hydrochloric acid.
Facile formations of ketals of α, α-dihaloacetophenones
Bovonsombat, Pakorn,McNelis, Edward
, p. 4123 - 4126 (2007/10/02)
Ketals of α,α-dihaloacetophenones are prepared in high yields from phenylethyne and N-halosuccinimide with catalytic quantities of p-toluenesulfonic acid.
Reactions of Terminal Alkynes with Iodine in Methanol
Heasley, Victor L.,Shellhammer, Dale F.,Heasley, Lynn E.,Yaeger, David B.,Heasley, Gene E.
, p. 4649 - 4652 (2007/10/02)
Terminal alkynes 1-hexyne (1), tert-butylacetylene (2), and phenylacetylene (3) react with iodine in methanol to give only 1,2-diiodoalkenes.If the reactions are carried out in the presence of silver nitrate, however, diiodo ketones (RC(O)CHI2) and substi
