749900-54-7Relevant academic research and scientific papers
Design and synthesis of benzo-lipoxin A4 analogs with enhanced stability and potent anti-inflammatory properties
Petasis, Nicos A.,Keledjian, Raquel,Sun, Yee-Ping,Nagulapalli, Kalyan C.,Tjonahen, Eric,Yang, Rong,Serhan, Charles N.
, p. 1382 - 1387 (2008/09/19)
A new class of chemically and metabolically stable lipoxin analogs featuring a replacement of the tetraene unit of native LXA4 with a substituted benzo-fused ring system have been designed and studied. These molecules were readily synthesized v
Benzo lipoxin analogues
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Page/Page column 20, (2008/06/13)
Benzolipoxin analogs, methods of their preparation and pharmaceutical compositions containing the compounds are provided. The compounds and compositions are useful in methods for treatment of various diseases, including, inflammation, autoimmune disease a
Generation of bromophenyllithium reagents from dibromobenzenes and addition to carbonyl and nitrile electrophiles
Caron, Stéphane,Do, Nga M.
, p. 1440 - 1442 (2007/10/03)
An evaluation of the mono-lithiation of all three regioisomers of dibromobenzene using n-butylithium was performed. The resulting aryllithium reagents were added to electrophiles such as ketones, aldehydes, nitriles and amides to afford the desired benzylic alcohols or ketones.
