749922-35-8

Basic information

• Product Name: 4-Quinolinol, 3-nitro-7-(phenylmethoxy)-
• CAS NO: 749922-35-8
• Molecular Formula: C16H12N2O4
• Molecular Weight: 296.282
• Mol File: 749922-35-8.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 4-Quinolinol, 3-nitro-7-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Quinolinol, 3-nitro-7-(phenylmethoxy)-(749922-35-8)
• EPA Substance Registry System: 4-Quinolinol, 3-nitro-7-(phenylmethoxy)-(749922-35-8)

Safety Data

• Hazardous Substances Data: 749922-35-8(Hazardous Substances Data)

Upstream product

• 1484-26-0 3-(benzyloxy)aniline 
• 749922-33-6 5-{[(3-benzyloxy)phenylimino]methyl}-2,2-dimethyl-[1,3]-dioxane-4,6-dione 
• 749922-34-7 7-(benzyloxy)quinolin-4-ol 

Downstream Products

• 749922-36-9 2-{[7-(benzyloxy)-3-nitroquinolin-4-yl]amino}ethanol 
• 847577-56-4 7-benzyloxy-2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline 
• 847577-54-2 7-benzyloxy-1-(2-methylpropyl)-2-propyl-1H-imidazo[4,5-c]quinoline 
• 850056-97-2 2-(4-amino-1-(2-methylpropyl)-2-propyl-1H-imidazo[4,5-c]quinolin-7-yloxy)-1-phenylethanone 
• 852802-34-7 tert-butyl 2-(4-amino-7-(benzyloxy)-2-{[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]methyl}-1H-imidazo[4,5-c]quinolin-1-yl)ethylcarbamate 
• 852801-93-5 tert-butyl 2-[4-amino-7-(benzyloxy)-2-({[(1-methylethylidene)amino]oxy}methyl)-1H-imidazo[4,5-c]quinolin-1-yl]ethylcarbamate 
• 852802-35-8 tert-butyl 2-[4-amino-2-[(aminooxy)methyl]-7-(benzyloxy)-1H-imidazo[4,5-c]quinolin-1-yl]ethylcarbamate 
• 852802-33-6 tert-butyl 2-[4-amino-7-(benzyloxy)-2-(chloromethyl)-1H-imidazo[4,5-c]quinolin-1-yl]ethylcarbamate 
• 847578-84-1 tert-butyl 2-[7-(benzyloxy)-2-(chloromethyl)-1H-imidazo[4,5-c]quinolin-1-yl]ethylcarbamate 
• 847578-82-9 tert-butyl 2-{[7-(benzyloxy)-3-nitroquinolin-4-yl]amino}ethylcarbamate 
• 847578-83-0 tert-butyl 2-[(3-amino-7-benzyloxyquinolin-4-yl)amino]ethylcarbamate 
• 847577-53-1 7-benzyloxy-N₄-(2-methylpropyl)quinoline-3,4-diamine 
• 905975-23-7 2-{[7-(benzyloxy)-3-nitroquinolin-4-yl]amino}ethanol 
• 874270-42-5 3-amino-7-benzyloxyquinolin-4-ol 

Relevant articles and documents

IMIDAZOQUINOLINE DERIVATIVES AND THEIR USE IN THERAPY

This invention relates inter alia to novel imidazoquinoline derivatives and their use in therapy, particularly as vaccine adjuvants. The imidazoquinoline derivatives are of formula (I):

CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS

Fused [1,2]imidazo[4,5-c] ring compounds (e.g., imidazo[4,5-c]quinolines, 6,7,8,9-tetrahydroimidazo[4,5-c]quinolines, imidazo[4,5-c]naphthyridines, and 6,7,8,9-tetrahydroimidazo[4,5-c]naphthyridines) with a -CH(-X1-R1)-group in the fused ring at the 1-position of the imidazo ring, pharmaceutical compositions containing the compounds, intermediates, methods of making the compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.

SUBSTITUTED FUSED [1,2]IMIDAZO[4,5-C] RING COMPOUNDS AND METHODS

Fused [1,2]imidazo[4,5-c] ring compounds, e.g., fused [1,2]imidazo[4,5-c]quinolines and [1,2]imidazo[4,5-c]naphthyridines, with a substituent, e.g., a substituted alkoxy substituent, at the 6, 7, 8, or 9-position, pharmaceutical compositions containing th