7501-57-7 Usage
Description
(3-methoxy-4-nitro-phenyl)-phenyl-methanone is a chemical compound with the molecular formula C14H11NO4. It is a yellow solid that is commonly used in organic synthesis and pharmaceutical research. (3-methoxy-4-nitro-phenyl)-phenyl-methanone contains a 3-methoxy-4-nitrophenyl group and a phenyl group connected by a methanone linker. It is known to have potential pharmacological activities and has been studied for its potential as an anti-inflammatory and anti-cancer agent. However, it is important to use caution when handling and working with this compound, as it may have potential hazards and risks associated with its use.
Uses
Used in Pharmaceutical Research:
(3-methoxy-4-nitro-phenyl)-phenyl-methanone is used as a research compound for its potential pharmacological activities. It is particularly studied for its potential as an anti-inflammatory and anti-cancer agent due to its chemical structure and properties.
Used in Organic Synthesis:
In the field of organic chemistry, (3-methoxy-4-nitro-phenyl)-phenyl-methanone serves as a valuable intermediate in the synthesis of various complex organic molecules. Its unique structure allows for further functionalization and modification, making it a versatile building block in the development of new compounds with specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 7501-57-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,5,0 and 1 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 7501-57:
(6*7)+(5*5)+(4*0)+(3*1)+(2*5)+(1*7)=87
87 % 10 = 7
So 7501-57-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H11NO4/c1-19-13-9-11(7-8-12(13)15(17)18)14(16)10-5-3-2-4-6-10/h2-9H,1H3
7501-57-7Relevant articles and documents
α-Chlorobenzylation of Nitroarenes via Vicarious Nucleophilic Substitution with Benzylidene Dichloride: Umpolung of the Friedel-Crafts Reaction
Brze?kiewicz, Jakub,Loska, Rafa?,Makosza, Mieczys?aw
, p. 8499 - 8508 (2018/06/25)
Readily available α,α-dichlorotoluenes enter a vicarious nucleophilic substitution (VNS) reaction with electron-deficient arenes to give α-chlorobenzylated nitrobenzenes, as well as six- and five-membered heterocycles. Oxidation of the initially formed α-chlorobenzylic carbanions instead of protonation results in formation of diaryl ketones, providing a means for overall nucleophilic C-H benzoylation of electron-deficient aromatic rings. Alternatively, benzoylated nitroarenes can be obtained via the reaction of isolated α-chlorodiarylmethanes with sodium azide.
Mandelic Acid as Synthetic Equivalent of Benzoyl Carbanion. Synthesis of Nitrobenzophenones
Blay, Gonzalo,Cardona, Luz,Fernández, Isabel,Michelena, Raquel,Pedro, José R.,Ramírez, Teresa,Ruiz-García, Rafael
, p. 2325 - 2328 (2007/10/03)
Nitrobenzophenones are prepared from a mandelic acid dioxolanone. The sequence starts with the aromatic nucleophilic substitution of the enolate of the dioxolanone onto p-fluoronitrobenzenes, followed by hydrolysis of the acetal moiety and oxidative decarboxylation of the resulting α-hydroxyacids. The whole sequence involves the use of mandelic acid as synthetic equivalent of the benzoyl carbanion.