750118-59-3Relevant academic research and scientific papers
A soluble-polymer system for the asymmetric transfer hydrogenation of ketones
Bastin, Stephanie,Eaves, Richard J.,Edwards, Christopher W.,Ichihara, Osamu,Whittaker, Mark,Wills, Martin
, p. 5405 - 5412 (2007/10/03)
The appropriate combination of methacrylate polymers permits the synthesis of a soluble polymer for use in ruthenium(II)-catalyzed asymmetric transfer hydrogenation reactions. Using a 7:3 copolymer of a poly(ethylene glycol) ester and a hydroxyethyl ester, a derived ruthenium(II)/norephedrine complex catalyses reduction of acetophenone in up to 95% yield and 81% ee.
