75026-25-4

Upstream product

• 247017-34-1 2,3,4-tri-O-benzoyl-β-L-arabinopyranosyl trichloroacetimidate-⁴C₁ 
• 75799-18-7 oleanolic acid 3-O-3)-O-α-L-rhamnopyranosyl-(1->2)>-α-L-arabinopyranoside 
• 120481-40-5 3-O-<α-L-rhamnopyranosyl(1->2)-α-L-arabinopyranosyl>-28-O-<β-D-glucopyranosyl(1->6)-β-D-glucopyranosyl>oleanolic acid 
• 36284-77-2 hederasaponin B 
• 75799-17-6 oleanolic acid 3-O-β-D-xylopyranosyl-(1-3)-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 72629-77-7 oleanolic acid 3-O-β-D-glucopyranosyl-(1-4)-β-D-xylopyranosyl-(1-3)-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 76742-94-4 oleanolic acid 3-O-β-D-glucopyranosyl-(1-4)-β-D-glucopyranosyl-(1-4)-β-D-xylopyranosyl-(1-3)-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 75799-17-6 oleanolic acid 3-O-β-D-ribopyranosyl-(1-3)-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 75799-17-6 oleanolic acid 3-O-β-D-xylopyranosyl-(1-3)-α-L-rhamnopyranosyl-(1-2)-α-L-arabinopyranoside 
• 72629-77-7 C₅₂H₈₄O₂₀ 
• 76742-94-4 oleanolic acid 3-O-β-D-glucopyranosyl-(1->4)-β-D-glucopyranosyl-(1->4)-β-D-ribopyranosyl-(1->3)-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranoside 
• 114906-75-1 ciwujianoside C₄ 
• 303114-51-4 oleanolic acid benzyl ester 
• 508-02-1 Oleanolic acid 

Downstream Products

• 73-34-7 L-rhamnose 
• 87-72-9 L-(+)-arabinose 
• 508-02-1 Oleanolic acid 

Relevant academic research and scientific papers

Antiproliferative triterpene saponins from Trevesia palmata

During the course of a study of plants of the family Araliaceae, antiproliferative activity was demonstrated by the crude saponin fraction of Trevesia palmata. After chromatographic purification, six new bisdesmosidic saponins (1-6), along with two known triterpenoid saponins, (7 and 8), were isolated. The structures of 1-6 were determined by 1H-1H correlation spectroscopy (COSY-DQF, 1D TOCSY, 2D HOHAHA, 1D ROESY) and 1H-13C (HSQC, HMBC) spectroscopy. The antiproliferative activity of compounds 1-8 and of their prosapogenins (2a-7a) prepared by alkaline hydrolysis, was evaluated using three continuous culture cell lines.

Synthesis and cytotoxicity of oleanolic acid trisaccharide saponins

An array of oleanolic acid-type saponins based on β-hederin has been synthesized in a linear or one-pot manner. The cell viability assays indicate that synthetic saponins show antiproliferation activities in three cancer cell lines with IC50 values of 2.4–15.1?μM and hederacolchiside A1 being the most potent. The results demonstrate that the type of terminal monosaccharides and linkage position have apparent effects on cytotoxicities and selectivities of these saponins against cancer cell lines tested. This study is helpful for future development of more potent anticancer leads.

Triterpenoid saponins from Anemone raddeana

Three new triterpenoid saponins, named raddeanoside R20 (1), raddeanoside R21 (2) and raddeanoside R22 (3), were isolated from the water soluble part of Anemone raddeana. The chemical structures of these new compounds were

Synthesis of β-hederin and Hederacolchiside A1: Triterpenoid saponins bearing a unique cytotoxicity-inducing disaccharide moiety

A facile synthetic approach toward oleanolic acid glycoside bearing α-l-rhamnopyranosyl-(1→2)-α-l-arabinopyranosyl moiety, a unique oligosaccharide that strongly induces antitumor activity of oleanane-type triterpenoid saponins, was developed. Based on th

Saponins from Leaves of Acanthopanax senticosus HARMS., Ciwujia; Structures of Ciwujianosides B, C1, C2, C3, C4, D1, D2 and E

Eleven triterpenoid saponins were isolated from the leaves of a Chinese folk medicine, Acanthopanax senticosus (RUPR. et MAXIM) HARMS.Of these compounds, three were identified as known saponins.The structures of eight new saponins named ciwujianosides B (1), C1, (2), C2 (3), C3 (4), C4 (5), D1 (6), D2 (7), and E (8) were elucidated to be as follows: (1), 3-O-α-rhamnopyranosyl-(1->2)-β-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (2), 3-O-α-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (3), 3-O-α-rhamnopyranosyl-(1->2)-α-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (4), 3-O-α-arabinopyranosyl oleanolic acid 28-O-α-rhamnopyranosyl-(1->4)-β-glucopyranosyl(1->6)-β-glucopyranosyl ester; (5), 3-O-α-rhamnopyranosyl-(1->2)-α-arabinopyranosyl oleanolic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (6), 3-O-α-arabinopyranosyl oleanolic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-β-glucopyranosyl(1->6)-β-glucopyranosyl ester; (7), 3-O-α-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-b-glucopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (8), 3-O-α-rhamnopyranosyl-(1->2)-α-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid.Keywords - Acanthopanax senticosus; Araliaceae; saponin; Chinese folk medicine; ciwujianoside; oleanolic acid glycoside; noroleanolic acid glycoside; 30-norolean-12,20(29)-dien-28-oic acid; ciwujia

TRITERPENE GLYCOSIDES AND THEIR GENINS FROM Thalictrum foetidum. I. THE STRUCTURE OF FOETOSIDE C

A new glycoside - foetoside C - has been isolated from the epigeal part of Thalictrum foetidum L. and, on the basis of chemical transformations and spectral characteristics its structure has been established as oleanolic acid 28-6)-O-β-D-glucopyranoside> 3-O-3)-O-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranoside>.