75057-36-2Relevant academic research and scientific papers
Aspects of the chemistry of functionalized 1-phenylpyrazoles available from 1,2-diaza-1,3-butadienes and 2-phenylazo-1,3-dicarbonyl compounds
Attanasi, Orazio A.,Filippone, Paolino,Fiorucci, Chiara,Mantellini, Fabio
, p. 3891 - 3894 (1999)
In the presence of sodium hydride, treatment of 1,2-diaza-1,3-butadienes with 2-phenylazo-1,3-dicarbonyl compounds gave rise to functionalized 1- phenylpyrazole derivatives in good to excellent yields. Pyrazolo[3,4-d]1,6- dihydropyridazin-6(2H)-one derivatives were obtained by the reaction of 5- methyl-4-methoxycarbonyl-3-acetyl-1-phenylpyrazole with different hydrazines.
Studies on Nitrile Imines : Synthesis of Pyrazoles Using Active Methylene Compounds
Tewari, R. S.,Parihar, P.
, p. 217 - 218 (2007/10/02)
A series of C-ethoxycarbonyl and C-acetyl derivatives of hydrazidoyl halides have been prepared and reacted with carbanions of active methylene compounds to afford substituted pyrazoles (II and III) in good yields.The formation of pyrazoles involves the alkylation of active methylene group by hydrazidoyl halides to give the acyclic hydrazones, which then undergo cyclization to give the corresponding pyrazoles.The structural assignments of the products are based on spectral and chemical evidences.
